Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam
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概要
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Purpose: To investigate the serotypes of adenovirus causing conjunctivitis in Hanoi, Vietnam.Design: Clinical diagnosis of adenoviral conjunctivitis and laboratory-based experimental study.Methods: We collected 21 conjunctival swabs from 21 different patients with a clinical presentation compatible with adenoviral conjunctivitis, in Hanoi, Vietnam. Immunochromatography and real-time polymerase chain reaction (PCR) were performed to detect human adenovirus (HAdV). The sequence of PCR products was analyzed to determine the serotype of HAdV.Results: Of 21 samples, HAdV DNA was detected in 14 samples (66.7%) by real-time PCR. The serotype analysis showed HAdV-8 in 11 samples (78.6%), HAdV-3 in two samples (14.3%), and HAdV-37 in one sample (7.1%). Of 11 HAdV-8 samples, one sample (9.1%) was prototype, and the other 10 samples (90.9%) had identical nucleotide sequence and were identified as a variant of HAdV-8.
- Elsevier Inc.の論文
著者
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Ohno Shigeaki
北海道大学 大学院医学研究科感覚器病学講座眼科学分野
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AOKI Koki
Aoki Eye Clinic
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Ohno Shigeaki
Department Of Ocular Inflammation And Immunology Hokkaido University Graduate School Of Medicine
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Ohno Shigeaki
Department Of Ophthalmology And Visual Sciences Hokkaido University Graduate School Of Medicine
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OHGUCHI Takeshi
Department of Ophthalmology, Hokkaido University Graduate School of Medicine
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