顆粒球輸血療法 : ドナーからの顆粒球採取を中心に(<特集>ドナーアフェレシスの現状と展開)

概要

論文の詳細を見る
Bacterial and fungal infections during the neutropenic period remain one of the most important causes of mortality in patients with hematologic malignancies. Several studies have shown that the transfusion of granulocyte concentrates, which are collected from healthy donors after mobilization with granulocyte colony-stimulating factor, result in a substantial increase in the patient's absolute neutrophil count. The efficacy of granulocyte transfusions in the improvement of clinical outcomes has been suggested in several studies, although large, randomized controlled trials should be conducted to corroborate this. The purpose of this review is to overview granulocyte transfusion therapy with a particular focus on granulocyte collection from healthy donors.
2012-10-31