High-dose-rate interstitial brachytherapy for tongue cancer : a radiological and biological study from the perspective of late complications

概要

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High-dose-rate interstitial brachytherapy (HDR-ISBT) is effective as a radical treatment for tongue cancer. The biggest issue regarding this treatment is, however, to reduce late complications that occur from six months after the treatment. In this study, the association between various patient factors and the occurrence of late complications was evaluated. The relationship between the total dose and local control rate was also determined. We found that the Brinkman index, which shows the smoking history, was higher in those who developed late complications than those who did not. No significant differences were seen in the other factors among the groups. There were no significant associations between the total dose and local control rate. Therefore, based on this study that demonstrated no differences in the local control rate regardless of the total dose, it was suggested that irradiation at a dose of 54 Gy is recommended to minimize the burden on the patients.