Effects of geraniin on the liver in rats I : effects of geraniin compared to ellagic acid, and gallic acid on hepatic injuries induced by CCl_4, D-galactosamine, and thioacetamide
スポンサーリンク
概要
- 論文の詳細を見る
The effects of geraniin from Geranium hunbergii Sieb. et Zucc, ellagic acid and gallic acid produced by hydrolysis of geraniin, on the experimental hepatic injuries induced by carbon tetrachloride, D-galactosamine, and thioacetamide in rats were examined . Geraniin and ellagic acid suppressed the carbon tetrachloride-, D-galactosamine-, and thioacetamide-induced hepatic injuries significantly. Geraniin also suppressed the increase in lipid peroxide level in the serum caused by inhalation of carbon tetrachloride. Histological observation confirmed that pretreatment with geraniin or ellagic acid had a protective effect against liver cell damage caused by carbon tetrachloride, D-galactosamine, and thioacetamide.
- 日本生薬学会の論文
- 1998-10-20
著者
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Nakanishi Y
Kinki Univ. Osaka Jpn
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Okuda T
Okayama Univ. Okayama Jpn
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Okuda Takuo
Faculty Of Pharmaceutical Sciences Okayama University
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Abe Hiroko
First Department Research Institute Of Oriental Medicine Kinki University
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Abe Hiroko
Research Institute Of Oriental Medicine Kinki University
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NAKANISHI Yuka
Research Institute of Oriental Medicine Kinki University
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ORITA Machiko
Research Institute of Oriental Medicine Kinki University
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Orita Machiko
First Department, Research Institute of Oriental Medicine, Kinki University
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Orita Machiko
First Department Research Institute Of Oriental Medicine Kinki University
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Okuda Takuo
Faculty of Pharmaceutical Science, Okayama University
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- Effects of geraniin on the liver in rats III : correlation between lipid accumulations and liver damage in CCl_4-treated rats
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- Effects of geraniin on the liver in rats I : effects of geraniin compared to ellagic acid, and gallic acid on hepatic injuries induced by CCl_4, D-galactosamine, and thioacetamide
- Hematological effect of geraniin in rat
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