J0204-1-6 椎間板組織の流動電位と圧縮応力の関係([J0204-1]バイオトライボロジー(1))

概要

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Intervertebral disc is constructed of nucleus pulposus (NP) and anulus fibrosus (AF). Intervertebral tissue contains a large amount of negatively-charged proteoglycan. When the tissue deforms, streaming potential is induced by liquid flow with positive ion. In this study, the relationship between streaming potential and applied stress in the bovine intervertebral tissue is investigated under confined compression. Column shaped specimens of 5.5 mm diameter and 3 mm thickness were prepared from several tissue of AF, NP and anulus - nucleus transition (AN) region. The loading direction of each specimen was oriented for spinal axial direction, and furthermore, circumferential and radial direction of spine in AF specimens. Although streaming potential was linearity increased by compressive stress in all specimens, linear coefficients k_e were different values in the tissue extracted region. Expect the case of axial loading of NP specimen, k_e showed higher values in faster compression rate condition. In the case of cyclic compression loading, streaming potential was linearly changed with compressive stress values regardless of tissue and load frequency. The linear coefficient k_e was not changed by cyclic number and loading time increases. The coefficient K_e at axial loading of NP specimen which had the highest proteoglycan density showed the highest value in the intervertebral specimens.
一般社団法人日本機械学会の論文
2010-09-04