J0206-2-6 計算生体力学を用いた大動脈瘤患者個別モデルの構築([J0206-2]生命体統合シミュレーション(2))

概要

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Aiming at establishing a simulation-based framework for predictive medicine we have developed a patient-specific aortic aneurysm model based on computational biomechanics. In this study, we construct two image-based three-dimensional patient-specific models of aortic aneurysms based on CT images of two patients. A multi-scale hemodynamic model is employed to couple these three-dimensional models with a closed-loop 0-1-dimension hemodynamic model for the whole cardiovascular system. The aortic aneurysm hemodynamics are then visualized in terms of streamlines, wall shear stresses and oscillatory shear index, and further analyzed with a specific focus on the relationship between the hemodynamics and the occurrence of the aortic aneurysm.
一般社団法人日本機械学会の論文
2010-09-04