A-7 アパタイトの結晶性がPLGA/アパタイト多孔体の骨形成に与える影響(インプラント・セメント・生体用セラミックスI,一般講演(口頭発表),第56回日本歯科理工学会学術講演会)

概要

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The cortical bone response to poly(lactide-co-glycolide)(PLGA)/apatite complexes with different levels of crystallnity was investigated. Apatites with different levels of crystallinity were prepared from Ca-EDTA complex, H_2O_2, H_3PO_4 and NH_4OH. Two porous PLGA/apatite composites, composite with low crystallinity apatite and composite with higher crystallinity apatite, were implanted into the cortical bone of rabbit tibiae for 12 weeks. Histological examinations revealed a better bone response for composite with low crystallinity apatite compared with PLGA and composite with higher crystallinity apatite. It revealed that the level of apatite crystallinity in the porous compsite influences bone response.
2010-09-20