749 フィプロインスポンジにおける軟骨細胞の挙動観察と定量評価(S01-2 細胞と組織のバイオメカニクス(2)-ミクロからマクロまで-,21世紀地球環境革命の機械工学:人・マイクロナノ・エネルギー・環境)

概要

論文の詳細を見る
Aiming to observe and evaluate cell behaviors in porous scaffold such as fibroin sponge, we developed a novel method where cells are cultured on a patterned substrate containing an array of pits which mimics culture environment in porous scaffold. Rabbit chondrocytes were seeded on the patterned substrates coated with fibroin (Fib group) or collagen type I (Col group), and cell behaviors such as aggregation and adhesion in the pit were observed and quantified. The results showed that projection area of the cells in the Fib group increased along with culture period, while that in the Col group showed no significant change.
社団法人日本機械学会の論文
2008-08-02