生体内環境設計のためのCA法を用いたES細胞-軟骨再生シミュレーションモデル(S02-1 生体組織のマルチスコープメカニクス(1).モデリングとメカニクス,S02 生体組織のマルチスコープメカニクス)

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This paper describes a tissue-regenerating model using a cellular automaton for Bio-environment designing. The model consists of identical cells which mechanically connect with each other. The mechanical relation state of each cell is calculated using FEM. The local rules are "death" which is induced by apoptosis, "birth" and "transition". In this model, each cell means not "cell" but tissue which have the information of an adapted function for the mechanical environment. The morphology and the function constructed by this model were formed autonomically through the way of selection on the mechanical environment. Results of in-vivo testing using ES cell transplantation were used as reference of this model.
社団法人日本機械学会の論文
2004-09-04