A Case of Pulmonary Benign Metastasizing Leiomyoma Occurring after Uterine Myomectomy
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概要
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Benign metastasizing leiomyoma (BML) is a very rare disease, and although it was reported as early as1939 to result from metastasis of benign uterine myoma to the lungs and lymph nodes, its pathology remainsobscure. Here, we describe a case of pulmonary BML occurring after uterine myomectomy in a42-year-old woman. She presented with a 2-week history of dry cough on exertion. Chest radiography andcomputed tomography( CT) revealed bilateral multiple nodular lesions. The patient had a history of uterinemyoma and previously underwent myomectomy. For definitive diagnosis, lung biopsy was performed byvideo associated thoracoscopic surgery. Histopathologic examination of biopsy specimens revealed pulmonaryBML occurring after uterine myomectomy. For treatment of the pulmonary BML, gonadotropin-releasinghormone was initially administered, and 1 month later the patient underwent complete hysterectomyand bilateral salpingo-oophorectomy. Chest CT 6 months after surgery showed that the size and number oflung multiple nodular lesions did not increase compared with those before surgery. In future studies, we aimto investigate a larger number of pulmonary BML cases, as well as establish specific treatments and investigatethe prognosis of the disease.Abbreviations:BML:benign metastasizing leiomyomaSS:Sjögren's syndromeCT:computed tomographyH&E:hematoxylin and eosinVATS:video associated thoracoscopic surgeryCA:carbohydrate antigenIg:immunoguloblina SMA:a smooth muscle actin
- 2010-07-25
著者
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Yasutsugu Fukushima
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Hirokuni Hirata
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Reika Maezawa
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Naruo Yoshida
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Yumeko Hayashi
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Ryo Arai
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Fumiya Fukushima
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Kumiya Sugiyama
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Kazuhiro Kurasawa
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Yoshiki Ishii
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Takeshi Fukuda
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University School of Medicin
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Ryo Arai
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Yoshiki Ishii
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Reika Maezawa
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Maezawa Reika
Department Of Allergy And Immunological Diseases Tokyo Metropolitan Komagome Hospital
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Naruo Yoshida
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Yumeko Hayashi
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Fumiya Fukushima
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Fukushima Fumiya
Department Of Internal Medicine Shioya General Hospital
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Kumiya Sugiyama
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Sugiyama Kumiya
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo University School Of Medicine
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Kumiya Sugiyama
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University
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Hirokuni Hirata
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Kazuhiro Kurasawa
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Kurasawa Kazuhiro
Department Of Internal Medicine Ii Chiba University School Of Medicine
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Yasutsugu Fukushima
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Fukushima Yasutsugu
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University
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Ishii Yoshiki
Department Of Biology Faculty Of Science Kobe University
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Takeshi Fukuda
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University School Of Medicin
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Fukuda Takeshi
Department Of Applied Chemistry And Biotechnology Graduate School Of Engineering University Of Fukui
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Takeshi Fukuda
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University
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Fumiya Fukushima
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University Japan
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Hirokuni Hirata
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University Japan
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Yasutsugu Fukushima
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University Japan
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Ishii Yoshiki
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Ishii Yoshiki
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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Hirata Hiroyuki
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Yoshida Naruo
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Hayashi Yumeko
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Arai Ryo
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Arai Ryo
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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Yoshida Naruo
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University
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Hayashi Yumeko
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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Sugiyama Kumiya
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Fukushima Fumiya
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Fukushima Fumiya
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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Fukushima Yasutsugu
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Hirata Hirokuni
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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Kurasawa Kazuhiro
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan
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Kurasawa Kazuhiro
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine
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