肺機能および加齢が肺癌肺切除の予後に及ぼす影響 : 75歳以上高齢者を中心に

概要

論文の詳細を見る
Between 1987 and 1998, a total of 686 non-small cell lung cancer patients underwent surgical treatment, we evaluated the preoperative pulmonary function of 101 (14.7%) elderly lung cancer patients aged 75 years and over who underwent surgical treatment and compared with that of 445 (64.9%) patients aged 74 years and younger. The absolute pulmonary function values of the elderly patients were lower than those of the non-elderly patients, suggesting reduced reserve pulmonary function capacity, and they were also shown to have reduced cardiopulmonary function by the unilateral pulmonary artery occlusion test. The elderly patients showed no difference between in the operative mortality rate and in 5-year survival rate for each stage of disease compared with the patients aged 74 years and younger (stage I; 64% vs 69%, II; 55 vs 41, III; 28 vs 16). There was no significant difference in 5-year survival rate according to whether restricted pulmonary function was present or not before surgical treatment. Surgical treatment is indicated in the elderly patients after strict estimation of their postoperative cardiopulmonary functions.
東京女子医科大学の論文
2000-12-25