Phosphorylation of Myosin Regulatory Light Chain by Myosin Light Chain Kinase, and Muscle Contraction
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概要
- 論文の詳細を見る
Not only muscle contraction, but also most cell movements depend on myosin - actin interaction using ATP. Many components of the contraction machinery are involved in the efficient coupling of energy source and force development. Among these, I have focused on myosin light chain kinase (MLCK) in this review. MLCK phosphorylates myosin regulatory light chain and controls all 3 types of muscle contraction: skeletal muscle, smooth muscle, and cardiac muscle. However, each muscle has specific MLCK and the role of MLCK in each muscle is different. This difference explains the specific role of each muscle in vivo and contributes to the activity of various force development in different ways in each tissue. Therefore, I also review the differences in the connection between each MLCK and muscle contraction in the 3 muscle types.
- 社団法人日本循環器学会の論文
- 2009-01-20
著者
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TAKASHIMA Seiji
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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Takashima Seiji
Department Of Cardiology Osaka University Graduate School Of Medicine
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Takashima Seiji
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine:department Of Mol
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