CLINICAL EVALUATION OF LEFT VENTRICULAR FUNCTION IN ACUTE MYOCARDIAL INFARCTION : Analysis of Factors Affecting Left Ventricular Function
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概要
- 論文の詳細を見る
The clinical significance of the possible factors which may affect the cardiac function and prognosis of the patients with acute myocardial infarction were evaluated in 112 patients with this disease. Patients were subdivided into 4 groups according to the levels of pulmonary capillary wedge pressure (PCWP) and left ventricular stroke work index (SWI): Group I (52 patients) PCWP<18 mmHg, SWI⩾30 g・m/m^2; Group II (18 patients) PCWP⩾18 mmHg, SWI⩾30 g・m/m^2; Group III (15 patients) PCWP<18 mmHg, SWI<30 g・m/m^2 ; Group IV (27 patients) PCWP⩾18 mmHg, SWI<30 g・m/m^2 . Immediate mortality rate (4 weeks after the onset of myocardial infarction) was 17.0% in all patients and Group IV had the highest mortality rate (48. 1%), in contrast to the lowest mortality rate (3.8%) in Group I. The episodes of previous myocardial infarction were noted more frequently in Group IV (74.1%) than in Groups I (7.7%) and II (11.1%) (p<0.001). Mean age in Group IV (68.0 :!: 5.2 (SE) years) was also significantly higher than those of the remaining 3 groups (p<0.001). In 55 patients without previous myocardial infarction, mean infarct size estimated from total released creatine phosphokinase (CPK) (CPK) in Group IV was largest among the 4 groups, although it was similar to that in Group II: 919.070.0 (SE) IU/ml in Group I, 1470.0126.0 in Group II, 958.0107.0 in Group III and 1493.0145.0 in Group IV. The number of involved coronary arteries differed significantly between Groups I and IV: in Group I involved coronary artery (75% narrowing) was absent or one at most, while in Group IV all 9 patients had at least one coronary lesion and 3 of 9 had triple vessel disease. In this study no significant difference was observed between the incidence of anterior and inferior myocardial infarctions in Groups I, III and IV. Thus, we conclude that age, previous myocardial infarction, infarct size and the number of involved coronary arteries may determine the cardiac function in acute phase of myocardial infarction and hence, immediate mortality of this disease.
- 社団法人日本循環器学会の論文
- 1982-06-20
著者
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Suga H
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Minamino Takazo
Department Of Internal Medicine And Therapeutics Osaka University Graduate School Of Medicine
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Hori Masatsugu
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Shimazu Takashi
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Minamino Takazo
The Division Of Cardiology Sakurabashi Watanabe Hospital
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Inoue Michitoshi
The First Dept. of Medicine, Osaka University
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HORI MASATSUGU
The First Department of Medicine, Osaka University Medical School
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Takashima Seiji
Department Of Cardiology Osaka University Graduate School Of Medicine
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Fukui Sugao
National Cardiovascular Center Research Institute
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Fukui Sugao
和泉市
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Fukui Sugao
Division Of Cardiology Sakurabashl Watanabe Hospital
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Fukui Sugao
The Cardiavascular Division, Sakurabashi Watanabe Hospital
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Minamino Takazo
The Cardiavascular Division, Sakurabashi Watanabe Hospital
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Shimazu Takashi
The First Department Of Medicine Osaka University School Of Medicine
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SATO HIDEYUKI
The Cardiovascular Division, Sakurabashi Watanabe Hospital
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HOSHIDA SHIRO
The Cardiovascular Division, Sakurabashi Watanabe Hospital
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OGITANI NOBUHISA
The Cardiovascular Division, Sakurabashi Watanabe Hospital
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SO KOYASU
The Cardiovascular Division, Sakurabashi Watanabe Hospital
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Sato Hideyuki
First Department Of Medicine Osaka University Medical School
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Inoue Michitoshi
The First Department Of Medicine Osaka University Medical School
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Minamino Takazo
The Cardiovascular Division Sakurabashi Watanabe Hospital
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Ohgitani Nobuhisa
The Cardiovascular Division Sakurabashi Watanabe Hospital
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So Koyasu
The Cardiovascular Division Sakurabashi Watanabe Hospital
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Harigae Satoko
Division Of Cardiology Yao Municipal Hospital
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Minamino Takazo
Cardiovascular Division Sakurabashi Watanebe Hospital
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Mandai Takashi
The Department Of Medicine And Geriatrics Osaka University Medical School
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Hoshida Shirou
The Cardiovascular Division Sakurabashi Watanabe Hospital.
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Hori Masatsugu
The First Department Of Medicine Osaka University Medicial School
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Ohgitani Nobuhisa
Sakurabashi-watanabe Hosp.
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Ohgitani Nobuhisa
First Dep. Of Surgery Radiology Osaka Univ. Med. School And Sakurabashi Watanabe Hospital
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Ogitani Nobuhisa
First Department Of Surgery Osaka Medical School University
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Hori Masatsugu
The First Department Of Medicine And The Department Of Medical Information Science
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Shimazu Takashi
The First Department Of Medicine Osaka University Medical School Osaka
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