Thyroid function in premature infants.
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概要
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The present study was performed using the simultaneous assays of free T4 and TSH levels in dried blood spots of filter paper for mass-screening of inborn errors of metabolism in order to clarify the thyroid function of premature infants. The subjects were divided in three groups: A group infants less than 1500 g at birth (n = 34, 27.4 +/- 2.6 weeks of gestational age), B group infants from 1500 to 2500 g at birth (n = 104, 35.6 +/- 2.4 weeks) and C group infants over 2500 g at birth (n = 490, 39.0 +/- 1.2 weeks). TSH levels were 4.51 +/- 3.03, 2.62 +/- 2.24 and 2.84 +/- 2.06 microU/ml in A, B and C group respectively and significant difference was recognized in group A and C. Free T4 levels were 0.71 +/- 0.42, 1.81 +/- 0.96 and 2.15 +/- 0.67 ng/dl, in group A, B and C respectively, and significant differences were recognized in all three groups. There was positive correlation between free T4 levels and gestational ages (Y = -2.413 +/- 0.11725X, r = 0.206, p less than 0.05).
- 神戸大学の論文
著者
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三好 正浩
北海道大学大学院獣医学研究科診断治療学講座臨床分子生物学教室:北海道立衛生研究所疫学部ウイルス科
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Mori Y
Department Of Biochemistry Tokyo College Of Pharmacy
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Nakao H
Department Of Infectious Diseases Research National Children's Medical Research Centre
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Sakurai T
Department Of Applied Biological Chemistry The University Of Tokyo:technology And Research Institute
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Miyoshi M
Department Of Environmental Health Graduate School Of Human Culture Nara Women's University
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Kobayashi K
Department Of Biological Sciences And Informatics Keio University
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Kodama S
Department Of Pediatrics Himeji Red Cross Hospital
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Komatsu M
Department Of Applied Chemistry Faculty Of Engineering Kyushu University
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Miyoshi M
Department Of Anatomy School O Medicine Fukuoka University
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Sakurai T
Hayashibara Biochemical Lab. Inc. Okayama Jpn
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