Effects of Xylooligosaccharides in Type 2 Diabetes Mellitus

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概要

• 論文の詳細を見る

• The purpose of this study was to evaluate the effect of xylooligosaccharide (XOS) on the blood sugar, lipids and oxidative status in type 2 diabetes mellitus (DM). A total of 26 outpatient subjects of Taichung Veterans General Hospital, Taiwan, with HbA1c levels between 7.0 and 10.0% and triglyceride <400mg/dL were enrolled in the present study. Subjects were supplemented with 4g/d XOS (n=12) or a placebo (n=14) for 8wk in a randomized double-blind clinical design. The results showed that the anthropometric values and nutrient intakes did not change during the experimental period. XOS supplementation not only reduced the glucose, HbA1c and fructosamine concentrations, but also decreased the levels of total cholesterol, low density lipoprotein (LDL) cholesterol, oxidized low density lipoprotein (ox-LDL) and apolipoprotein B. The activity of catalase of the erythrocyte sample decreased in the XOS group, but not the activities of superoxide dismutase and glutathione peroxidase. In conclusion, the dietary supplementation with XOS for 8wk was effective in improving the blood sugar and lipids in type 2 diabetes, indicating that XOS-containing diets might be beneficial to DM subjects.

• 日本ビタミン学会の論文

著者

• Chen Wei

  Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine

• SHEU Wayne

  Division of Endocrinology and Metabolism, Department of Medicine, Veterans General Hospital

• Sheu Wayne

  Division Of Endocrinology And Metabolism Department Of Internal Medicine Taichung Veterans General H

• CHAN Yin-Ching

  Department of Food and Nutrition, Providence University

• LEE I-Te

  Division of Endocrinology and Metabolism, Taichung Veterans General Hospital

• Lee I-te

  Division Of Endocrinology And Metabolism Department Of Internal Medicine Taichung Veterans General H

• Chan Yin-ching

  Department Of Food And Nutrition Providence University

• Chan Yin-ching

  Dep. Of Food And Nutrition Providence Univ.

• Chen Wei

  Department Of Food And Nutrition Providence University

• Chen Wei

  Department Of Chemical Engineering Nagoya University

• Chen Wei

  Department of Cell Biology, Third Military Medical University

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