Elderly Patients With Minimal Common Carotid Atherosclerosis Not Infrequently Have Severe Coronary Atherosclerosis and Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Background The presence of discordances between common carotid and coronary atherosclerosis in the same individual has not been previously reported. Methods and Results The subjects of the present study were 1,518 consecutive autopsy cases at a general geriatric hospital. All were aged 60 years or older (821 men, 697 women) with an average age of 80 years. The atherosclerotic index of the common carotid artery (CC-AI) and coronary stenotic index (CSI) were semi-quantitatively evaluated. The simple correlation coefficient between the CC-AI and CSI was 0.456 (p<0.0001). Among 689 cases with minimal common carotid atherosclerosis (CC-AI ≤2), 74 (11%) had severe coronary atherosclerosis (CSI ≥12), 68 (10%) had coronary heart disease, and 80 (12%) had pathologically-verified myocardial infarction (MI). Among those with minimal common carotid atherosclerosis, the serum total cholesterol level, diabetes mellitus, and history of smoking were significantly higher or more frequent in cases with a CSI ≥12 than in the patients with a CSI<12. Conclusions A considerable proportion of cases with minimal common carotid atherosclerosis had severe coronary atherosclerosis and MI. This discordance can potentially lead to an underestimation of coronary risks if normal common carotid morphology is obtained by ultrasound.
- 社団法人日本循環器学会の論文
- 2008-11-20
著者
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SAWABE Motoji
Department of Pathology, Tokyo Metropolitan Geriatric Hospital
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ARAI Tomio
Department of Pathology, Tokyo Metropolitan Geriatric Hospital
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TANAKA Noriko
Department of Biostatistics, Harvard School of Public Health
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Sakai Makoto
Department Of Pathology Tokyo Metropolitan Geriatric Hospital
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Harada Kazumasa
Department of Cardiology, Tokyo Metropolitan Geriatric Hospital
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Harada Kazumasa
Department Of Internal Medicine Tokyo Metropolitan Geriatric Hospital
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Harada Kazumasa
Department Of Cardiology Tokyo Metropolitan Geriatric Hospital
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Sawabe Motoji
Department Of Pathology Tokyo Metropolitan Geriatric Hospital
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Ozawa Toshio
Department of Medicine & Geriatrics, Kochi Medical school
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Tanaka Noriko
Department Of Biostatistics Harvard School Of Public Health
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CHIDA Kouji
Department of Cardiology, Tokyo Metropolitan Geriatric Medical Center
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Sawabe Motoji
Tokyo Metropolitan Geriatric Hospital
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Hamamatsu Akihiko
Department of Pathology, Tokyo Metropolitan Geriatric Hospital
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Hamamatsu Akihiko
Department Of Pathology Tokyo Metropolitan Geriatric Hospital
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Chiba Kazuo
Tokyo Metropolitan Geriatric Hospital
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Chida Kouji
Department Of Pathology Tokyo Metropolitan Geriatric Hospital
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Chida Koji
Department Of Nuclear Medicin Tokyo Metoropolitan Geriatric Hospital
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Arai Tomio
Human Tissue Research Group Tokyo Metropolitan Institute Of Gerontology And Department Of Pathology
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Ozawa Toshio
Department Of Internal Medicine Tokyo Metropolitan Geriatric Hospital
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Sawabe M
Department Of Pathology Tokyo Metropolitan Geriatric Hospital
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Sawabe Motoji
Department Of Pathology Tokyo Metropolitan Geriatric Medical Center
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Sawabe Motoji
Department Of Clinical Pathology Tokyo Metropolitan Geriatric Medical Center
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Arai Tomio
Department Of Clinical Pathology Tokyo Metropolitan Institute Of Gerontology
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Chida Koji
Department Of Internal Medicine Tokyo Metropolitan Geriatric Medical Center
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Arai Tomio
Deparment Of Pathology Tokyo Metropolitan Geriatric Hospital
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Ozawa Toshio
Department Of Geriatrics Faculty Of Medicine University Of Tokyo
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Hamamatsu Akihiko
Department Of Forensic Pathology Tokyo Medical Examiner's Office
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Arai Tomio
Department Of Pathology Tokyo Metropolitan Geriatric Center
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Chida Kouji
Divisions Of Cardiology Tokyo Metropolitan Geriatric Hospital:department Of Clinical Pathology Tokyo
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Ozawa Toshio
Department Of Geriatric Medicine Kochi Medical School
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Tanaka Noriko
Research And Development Program For Next-generation Computational Science
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Sawabe Motoji
Department Of Clinical Pathology Tokyo Metropolitan Institute Of Gerontology
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