Synthesis of Dibenzofurans Directly from Aryl Halides and ortho-Bromophenols via One-Pot Consecutive SNAr and Intramolecular Palladium-Catalyzed Aryl-Aryl Coupling Reactions

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概要

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• A series of dibenzofurans were efficiently and conveniently synthesized via one-pot consecutive C (sp^2)-O bond formation reaction (SNAr) in the presence of anhydrous K_2CO_3, followed by C(sp^2)-C (sp^2) bond formation reaction (intramolecular palladium-catalyzed aryl-aryl coupling reaction) between aryl halides and ortho-bromophenols. The desired dibenzofurans were obtained in 32-99% isolated yields.

• 公益社団法人日本薬学会の論文
• 2008-10-01

著者

• Xu Hui

  Laboratory of Pharmaceutical Synthesis, College of Sciences, Northwest A & F University

• FAN Ling-Ling

  Laboratory of Pharmaceutical Synthesis, College of Sciences, Northwest A & F University

• Fan Ling-ling

  Lab. Of Pharmaceutical Synthesis Coll. Of Sciences Northwest A&f Univ.

• Fan Ling-ling

  Laboratory Of Pharmaceutical Synthesis College Of Sciences Northwest A & F University

• Xu Hui

  Laboratory Of Pharmaceutical Synthesis College Of Sciences Northwest A & F University

• Xu Hui

  Laboratory Of Pharmaceutical Synthesis College Of Sciences Northwest A&f University

• Xu Hui

  Laboratory Of Lmmunology National Eye Lnstitute National Lnstitutes Of Health

• Fan Ling-Ling

  Laboratory of Pharmaceutical Design & Synthesis, College of Sciences, Northwest A&F University

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