Benzylpiperazine Derivatives. IV. : Syntheses and Cerebral Vasodilating Activities of 1-Benzyl-4-diphenylmethyl-piperazine Derivatives(Medeicinal Chemistry,Chemical)
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概要
- 論文の詳細を見る
A series of 1-benzyl-4-diphenylmethylpiperazines was prepared and tested for cerebral vasodilating activity. Among the compounds with stronger potency and longer-lasting action than papaverine, the most potent analog 19 (KB-2796) was selected for further study. Some pharmacological properties of 19 are presented.
- 公益社団法人日本薬学会の論文
- 1987-08-25
著者
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ITO KEIZO
Pharmaceuticals Research Center, Kanebo Ltd.
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TSUKAMOTO GORO
Pharmaceuticals Research Center, Kanebo Ltd.
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Ohtaka H
Kyoritsu College Of Pharmacy
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Ito Keizo
Pharmaceuticals Research Center Kanebo Ltd.
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Tsukamoto G
Pharmaceuticals Research Center Kanebo Ltd.
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Tsukamoto Goro
Pharmaceuticals Research Center Kanebo Ltd.
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OHTAKA HIROSHI
Pharmaceuticals Research Center, Kanebo Ltd.
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KANAZAWA TOSHIRO
Pharmaceuticals Research Center, Kanebo Ltd.
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KANAZAWA Tsutomu
(Present address)Amino Up Chemical Co., Ltd.,
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Kanazawa T
(present Address)amino Up Chemical Co. Ltd.
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