Synthesis of 2-Substituted 5-(1-Oxido-4-pyridyl)- and 5-(1-Oxido-2-pyridyl)-1,3,4-thiadiazole Derivatives by Substitution of 2-Methylsulfonyl Group with Various Nucleophiles(Organic,Chemical)
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概要
- 論文の詳細を見る
The synthesis of 2-substituted 5-(1-oxido-4-pyridyl)-(4a-10a) and 5-(1-oxido-2-pyridyl)-1,3,4-thiadiazole derivatives (4b-10b) by substitution reaction of 5-(1-oxido-4-pyridyl)- (3a) and 5-(1-oxido-2-pyridyl)-2-methylsulfonyl-1,3,4-thiadiazole (3b) is described. 5-(1-Oxido-4-pyridyl)- (9a) and 5-(1-oxido-2-pyridyl)-1,3,4-thiadiazole (9b) could be reduced with sodium dithionite to 2-(4-pyridyl)- (11c) and 2-(2-pyridyl)-1,3,4-thiadiazole (11d).
- 公益社団法人日本薬学会の論文
- 1987-03-25
著者
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豊岡 康平
Faculty of Pharmaceutical Sciences, University of Tokushima
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川嶋 康司
Faculty of Pharmaceutical Sciences, University of Tokushima
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久保田 晴寿
Faculty of Pharmaceutical Sciences, University of Tokushima
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久保田 晴寿
徳島大学薬学部
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豊岡 康平
Faculty Of Pharmaceutical Sciences University Of Tokushima
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久保田 晴寿
Faculty Of Pharmaceutical Sciences University Of Tokushima
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川嶋 康司
Faculty Of Pharmaceutical Sciences University Of Tokushima
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