Irradiation System for HIMAC

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概要

• 論文の詳細を見る

• Clinical trials of carbon radiotherapy started at HIM AC in 1994 using three treatment rooms and four beam ports, two horizontal and two vertical. The broad beam method was adopted to make a three-dimensionally uniform field at an isocenter. A spot beam extracted from an accelerator was laterally spread out by using a pair of wobbler magnets and a scatterer. A bar ridge filter modulated the beam energy to obtain the spread out Bragg peak (SOBP). The SOBP was designed to be flat in terms of the biological dose based on the consideration that the field consisted of various beams with different LET. Finally, the field of 20 cm in diameter with ± 2.5% uniformity was formed at the isocenter. The width of the maximum SOBP was 15 cm. When treating the lung or liver, organs that move due to breathing, the beam was irradiated only during the expiration period in a respiration-gated irradiation method. This reduced the treatment margin of the moving target. In order to prevent normal tissues adjacent to the target volume from irradiation by an unwanted dose, a layer-stacking method was developed. In this method, thin SOBP layers which have different ranges were piled up step by step from the distal end to the entrance of the target volume. At the same time, a multi-leaf collimator was used to change the aperture shape to match the shape of each layer to the cross-sectional shape of the target. This method has been applied to rather large volume cancers including bone and soft-tissue cancers. Only a few serious problems in the irradiation systems have been encountered since the beginning of the clinical trials. Overall the systems have been working stably and reliably.

• 日本放射線影響学会の論文

著者

• Tadokoro Masahiro

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• MINOHARA Shinichi

  Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit

• KANEMATSU Nobuyuki

  Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit

• NODA Koji

  Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit

• ENDO Masahiro

  Department of Mechanical Engineering, Fukuoka University

• Nishimura K

  茨城県立医療大学

• Kanai T

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Kanai Tatsuaki

  茨城県立医療大学 放射線技術科学科

• KANAI Tatsuaki

  NIRS

• MINOHARA Shinichi

  Div. Accelerator Phys. Eng.

• Noda Koji

  Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut

• Endo Masahiro

  Department Of Cardiovascular Surgery Toranomon Hospital

• Kanai T

  National Institute Of Radiological Sciences

• Kanai Tatsuaki

  Department Of Accelerator And Medical Physics Research Center For Charged Particle Therapy National

• Kanai Tatsuaki

  Division Of Accelerator Physics And Engineering National Institute Of Radiological Sciences

• Kanai Tatsuaki

  Department Of Medical Physics National Institute Of Radiological Sciences

• KOMORI Masataka

  Department of Accelerator and Medical Physics, National Institute of Radiological Sciences

• TORIKOSHI Masami

  Department of Accelerator and Medical Physics, National Institute of Radiological Sciences

• Kanazawa Mitsutaka

  National Institute of Radiological Sciences

• Itoh Hiroko

  Department of Biology, Faculty of Science, Hokkaido University

• Torikoshi Masami

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Komori Masataka

  筑波大学 数理物質科学研究科電子･物理工学専攻

• Endou Masahiro

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Mori Shinichiro

  Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut

• Kamata Tadashi

  Research Center Hospital For Charged Particle Therapy National Institute Of Radiological Sciences

• Komori Masataka

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Noda Koji

  放射線医学総合研究所重粒子医科学センター 医学物理部

• Itoh Hiroko

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Torikoshi Masami

  放射線医学総合研究所重粒子医科学センター 医学物理部

• KANAZAWA Mitsukata

  Department of Accelerator and Medical Physics, National Institute of Radiological Sciences

• MIYAHARA Nobuyuki

  Department of Accelerator and Medical Physics, National Institute of Radiological Sciences

• Kanai Tatsuaki

  Div. Acce. Res. Natl. Inst. Radiol Sci.

• Kanematsu Nobuyuki

  Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut

• Kanazawa M

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Minohara Shinichi

  Research Center For Particle Therapy National Institute Of Radiological Sciences

• Minohara Shinichi

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Kanai Tatsuaki

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Miyahara Nobuyuki

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Noda Koji

  Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences

• Endo Masahiro

  Department Of Cardiovascular Surgery The Heart Institute Of Japan Tokyo Women's Medical Univers

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