New Accelerator Facility for Carbon-Ion Cancer-Therapy
スポンサーリンク
概要
- 論文の詳細を見る
The first clinical trial with carbon beams generated from HIMAC was conducted in June 1994. The total number of patients treated as of December 2006 was in excess of 3,000. In view of the significant growth in the number of protocols, the Japanese government gave its approval for carbon-ion therapy at NIRS as an advanced medical technology in 2003. The impressive advances of carbon-ion therapy using HIMAC have been supported by high-reliability operation and by advanced developments of beam-delivery and accelerator technologies. Based on our ten years of experience with HIMAC, we recently proposed a new accelerator facility for cancer therapy with carbon ions for widespread use in Japan. The key technologies of the accelerator and beam-delivery systems for this proposed facility have been under development since April 2004, with the main thrust being focused on downsizing the facility for cost reduction. Based on the design and R&D studies for the proposed facility, its construction was begun at Gunma University in April 2006. In addition, our future plans for HIMAC also include the design of a new treatment facility. The design work has already been initiated, and will lead to the further development of therapy using HIMAC. The following descriptions give a summary account of the new accelerator facility for cancer therapy with carbon ions and of the new treatment facility at HIMAC.
- 日本放射線影響学会の論文
著者
-
鎌田 正
北海道大学医学部放射線科
-
Murakami Takeshi
Department of Physics, Tokyo Institute of Technology
-
Tadokoro Masahiro
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
MINOHARA Shinichi
Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit
-
TAKEI Yuka
Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit
-
FURUKAWA Takuji
Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit
-
NODA Koji
Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Instit
-
Kanai T
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Kanai Tatsuaki
茨城県立医療大学 放射線技術科学科
-
Sato Shinji
Department of Sport and Health Science, Osaka Sangyo University
-
Fujisawa Takashi
Department of Internal Medicine, Harima Hospital of Ishikawajima-Harima Heavy Industries, Health Ins
-
KANAI Tatsuaki
NIRS
-
MINOHARA Shinichi
Div. Accelerator Phys. Eng.
-
Yamada S
Electronic Imaging And Devices Research Laboratory Fuji Xerox
-
Yamada So
Electronic Imaging And Devices Research Laboratory Fuji Xerox Co. Lid.
-
Noda Koji
Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut
-
Takei Yuka
Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut
-
Yamada Shoji
Shizuoka Institute Of Science And Technology
-
Kanai T
National Institute Of Radiological Sciences
-
Kanai Tatsuaki
筑波大学 数理物質科学研究科電子・物理工学専攻
-
Kanai Tatsuaki
Department Of Accelerator And Medical Physics Research Center For Charged Particle Therapy National
-
Kanai Tatsuaki
Department Of Medical Physics National Institute Of Radiological Sciences
-
IWATA Yoshiyuki
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
KANAZAWA Mitsutaka
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
KITAGAWA Atsushi
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
KOMORI Masataka
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
MURAMATSU Masayuki
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
TASHIRO Mutsumi
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
TORIKOSHI Masami
Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
-
YAMADA Satoru
Research Center for Heavy Ion Medicine, Gunma University
-
YUSA Ken
Research Center for Heavy Ion Medicine, Gunma University
-
Kanazawa Mitsutaka
National Institute of Radiological Sciences
-
Yusa Ken
Research Center For Heavy Ion Medicine Gunma University
-
Torikoshi Masami
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Komori Masataka
筑波大学 数理物質科学研究科電子・物理工学専攻
-
Mori Shinichiro
Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut
-
Kamata Tadashi
Research Center Hospital For Charged Particle Therapy National Institute Of Radiological Sciences
-
Iwashita Yoshihisa
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Furukawa Takuji
Department Of Accelerator And Medical Physics Research Center For Particle Therapy National Institut
-
Kitagawa Atsushi
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Kitagawa Atsushi
放射線医学総合研究所重粒子医科学センター 医学物理部
-
Muramatsu Masayuki
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Komori Masataka
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Noda Koji
放射線医学総合研究所重粒子医科学センター 医学物理部
-
Yamada S
Research Center For Heavy Ion Medicine Gunma University
-
Torikoshi Masami
放射線医学総合研究所重粒子医科学センター 医学物理部
-
Murakami Takeshi
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Tashiro Mutsumi
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Fujisawa Takashi
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Kanai Tatsuaki
Div. Acce. Res. Natl. Inst. Radiol Sci.
-
Kanazawa M
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Minohara Shinichi
Research Center For Particle Therapy National Institute Of Radiological Sciences
-
Minohara Shinichi
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Kanai Tatsuaki
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Sato Shinji
Department Of Astrophysics Nagoya University
-
Yamada Satoru
Research And Development Division Bio-giken Inc.
-
Noda Koji
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
-
Sato Shinji
Department Of Accelerator And Medical Physics National Institute Of Radiological Sciences
関連論文
- CT-based 3D Dose-Volume Parameter of the Rectum and Late Rectal Complication in Patients with Cervical Cancer Treated with High-Dose-Rate Intracavitary Brachytherapy
- 前立腺癌に対する重粒子線治療 (AYUMI 重粒子線治療--最新治療エビデンス)
- SF-039-5 FDG-PETを用いた食道癌術前治療の組織学的CR判定 : 重粒子線vs.放射線(食道癌2,サージカルフォーラム,第109回日本外科学会定期学術集会)
- DP-086-7 食道扁平上皮癌に対する重粒子線治療と放射線化学療法施行例におけるFDG-PETによる効果判定(第108回日本外科学会定期学術集会)
- P-272 肺癌炭素線治療後長期生存例の治療前後のCT画像の変化についての検討(放射線療法,第49回日本肺癌学会総会号)
- 末梢型I期非小細胞肺癌に対する短期少分割炭素イオン線照射(荷電粒子線と定位照射, 第46回 日本肺癌学会総会)
- 14.前立腺癌重粒子線治療後の直腸出血に対するリスク因子解析(一般演題(有害事象および緩和),第35回群馬放射線腫瘍研究会抄録)
- P-10 重粒子線治療を行った非小細胞肺癌症例を対象とした血清プロテオーム解析(一般演題(ポスター) 分子生物学,第48回日本肺癌学会総会)
- Horizontal CTによる患者位置決め
- 168 水平置きCTシステムの開発
- WS-9-6 直腸癌術後骨盤内局所再発に対する重粒子線治療(第107回日本外科学会定期学術集会)
- 直腸癌術後局所再発に対する重粒子線治療(大腸36, 第60回日本消化器外科学会総会)
- QUADRANTECTOMY AND RADIOTHERAPY FOR EARLY STAGE BREAST CANCER : RESULTS OF 51 PATIENTS WHOSE TREATMENT PLANNING WAS DONE WITH A CT-BASED-PLANNING SYSTEM (RTCT)
- 頭頸部腫瘍の放射線治療におけるSMALL FIELD BOOST
- 子宮頚癌における傍大動脈リンパ節照射の治療成績
- 中咽頭扁平上皮癌放射線治療における PCNA (Proliferating Cell Nuclear Antigen) 標識率の予後因子としての意義
- A New High-Spin Isomer in ^Sm
- 自己組織化マップを用いた複数MRI画像からの腫瘍診断支援システムの開発
- WS-3-9 直腸癌術後の骨盤内局所再発に対する重粒子線治療(ワークショップ3 再発腫瘍の外科治療法および集学的治療方針-大腸・肛門-,第63回日本消化器外科学会総会)
- DP-158-1 直腸癌術後骨盤内局所再発に対する重粒子線治療の第II相試験(第108回日本外科学会定期学術集会)
- PD-5-6 直腸癌術後局所再発に対する重粒子線治療(パネルディスカッション5 切除不能・再発大腸癌に対する治療のベストチョイスは?,第62回日本消化器外科学会定期学術総会)
- がんの重粒子線治療
- PD-13-8 直腸癌術後局所再発に対する重粒子線治療の第I/II相試験
- 直腸癌術後再発に対する重粒子線治療の第I/II相試験
- Carbon Ion Radiotherapy : Clinical Experiences at National Institute of Radiological Science (NIRS)
- 心臓原発血管肉腫に対する新しい治療法 : 炭素粒子放射線治療が有効であった1症例(日本循環器学会関東甲信越地方会第187回学術集会)
- Heavy ion CT system based on measurement of residual range distribution
- Heavy Ion CT Reconstructed from Residual Range Distribution Measured by Range Shifter and Fluoroscopy System
- Sensitometric Properties in Heavy Ion Radiography
- Residual range distribution measured by heavy ion radiography
- 早期癌の重粒子線治療 (特集 放射線治療--切らずに治す早期の癌(2))
- 子宮癌に対する重粒子線治療の現状
- 食道癌に対する粒子線治療
- Comparisons of the Skeletal Muscle Metabolic Abnormalities in the Arm and Leg Muscles of Patients With Chronic Heart Failure
- PE-381 Exposure to Pressure Stimulus Enhances Aerobic Metabolism in L6 Cultured Myocytes(Exercise Test/Cardiac Rehabilitation 7 (IHD) : PE65)(Poster Session (English))
- Optimal Weight Reduction Pace to Improve Cardiovascular Risks and C-Reactive Protein Levels
- Exercise Training and Weight Reduction Decreased C-Reactive Protein Levels in Overweight Women
- 悪性軟部腫瘍の診断と治療-放射線療法の適応は 重粒子線治療の今
- 重粒子線を用いたがん治療の現状と展望 (特集 がん放射線療法の進歩と展望)
- PD-8-6 切除非適応後腹膜軟部悪性腫瘍に対する炭素イオン線治療の可能性(第108回日本外科学会定期学術集会)
- Isomer Decay of ^Ce Studied by Gas Filled Recoil Ion Separator
- Static Mechanical Pressure Stress Causes Cell Proliferation through an Activation of NF-Kappa B in Human Aortic Smooth Muscle Cells
- Static pressure induces an activation of c-Src with cell proliferation in human aortic smooth muscle cells
- Proton dosimetry intercomparison based on the ICRU protocol
- Evaluation of Late Radiation Damage of Normal Tissues in Mouse Hind Legs after Irradiation with Carbon Beams
- RBE and Dose Distribution of Heavy Ion Beams.
- Dose response relations in acute cell death of pancreatic islets after irradiation of golden hamster with X-ray ,7OMeV proton and 290MeV carbon beams.
- Morphological Evaluation of Normal Tissue Damage after Neon Beam Irradiation in Mouse Hind Legs
- Scintillation Detector System for Heavy Ion CT
- Precise Measurement of Range of Heavy Charged Particles
- LET spectra of HZE particle beams in a tissue-equivalent material
- Spectra of Linear Energy Transfer vs. Relative Biological Effectiveness for Accelerated Heavier Ions upon Clonogenic Survival of V79 Cells
- Analysis of Mutations in the Human HPRT Gene induced by High LET Heavy-ion Irradiation
- Skin Shrinkage Caused by Neon-20 and Carbon-12
- Dosimetry for heavy-ion radiation fields of argon, iron and kripton beams.
- A Comparison of Differences in the Gene Expression Profiles of Phorbol 12-myristate 13-acetate Differentiated THP-1 Cells and Human Monocyte-derived Macrophage
- The Gene Expression Profile of Human Umbilical Vein Endothelial Cells Stimulated by Tumor Necrosis Factor α Using DNA Microarray Analysis
- Effect of Heavy Ion Exposure on Cell Cycle Progression.
- Effect of Exposure of Heavy Ion Beams on G2 Arrest.
- シェルを用いた放射線治療計画用CTシステム画像とMRIの重ね合わせの試み
- A Novel Zinc Finger Protein mRNA in Human Umbilical Vein Endothelial Cells is Profoundly Induced by Tumor Necrosis Factor α
- New Accelerator Facility for Carbon-Ion Cancer-Therapy
- Mutation induction on normal human cells by split dose irradiation with carbon-ion beams
- Cell death on human cells by split dose irradiation with carbonion beams.
- 161 胆管癌に対するイリジュウム針腔内照射の応用(第25回日本消化器外科学会総会)
- 涙腺腫瘍に対する重粒子線治療 (特集 眼窩腫瘍アップデート)
- Heavy ion radiography
- 61. 食道表在癌に対する放射線治療(第994回千葉医学会例会・千葉大学医学部第二外科例会)
- Initial Symptoms of Acute Radiation Syndrome in the JCO Criticality Accident in Tokai-mura
- Treatment of Patients who were Severely Exposed to Neutron and Gamma Radiation in the Recent Criticality Accident in Tokaimura
- S3-7 小型末梢非小細胞肺癌に対する非外科的根治術 : 重粒子(炭素イオン)線治療(小型肺癌の診断と治療, 第30回日本呼吸器内視鏡学会学術集会)
- Development of multichanel Ion Chamber for measurement of 3 dimensional dose Distributions of Heavy-Ion Therapeutic Beam in patients
- Reconstruction of Dose Calculation on CT-Image from Dose Distribution in Water Phantom
- A Proton Dose Calculation Code for Treatment Planning Based on the Pencil Beam Algorithm
- Analysis of the Penumbra for Uniform Irradiation Fields Delivered by a Wobbler method
- 19.前立腺癌に対する重粒子線治療(第2相臨床試験)(一般演題(治療成績),第34回群馬放射線腫瘍研究会抄録)
- 22.眼球脈絡膜悪性黒色腫に対する炭素イオン線治療(新たな治療の試み,一般演題,第33回群馬放射線腫瘍研究会抄録)
- 13. 前立腺癌に対する重粒子線治療(第31回群馬放射線腫瘍研究会抄録)
- 5. 前立腺癌の重粒子線治療におけるQOL調査(第31回群馬放射線腫瘍研究会抄録)
- 新しい医療技術 重粒子線(炭素イオン線)を用いた転移性骨腫瘍の治療
- The Generation of Monoclonal Antibodies against Human Peroxisome Proliferator-activated Receptors(PPARs)
- AGE-RELATED ALTERATIONS IN ADENYLYL CYCLASE SYSTEM OF RAT HEARTS
- -P217- DEVELOPMENT- AND AGE-RELATED ALTERATIONS IN GUANINE NUCLEOTIDE-BINDING PROTEIN (Gs, Gi) OF RAT MYOCARDIUM
- The isoeffect dose of carbon ions depends on LET and fractionation
- Reoxygenation of artificially hypoxic tumors
- II-14. OK-432の局所投与と放射線の併用療法が奏功した食道癌術後縦隔再発の1例(II. 再発食道癌を巡る諸問題)
- Clinical Results of Carbon Ion Radiotherapy at NIRS
- 放射線治療計画用CT装置の開発 : スリットスキャノグラフィーの利用 : 第44回総会学術研究発表抄録 : 治療-10治療計画
- 11. 放射線治療計画用CT装置の開発(その1) : CR画像を用いたプランニング : 北海道部会 : 治療
- 263.放射線治療計画用CT装置の開発 : スリットスキャノグラフィーの利用 : 第44回総会学術大会会員研究発表予稿
- 粒子線治療--重粒子線 (頭頸部の診断と治療update) -- (放射線治療)
- Specification of Carbon Ion Dose at the National Institute of Radiological Sciences (NIRS)
- 放射線療法 重粒子線治療 (前立腺癌(第2版)--基礎・臨床研究のアップデート) -- (臨床 前立腺癌の治療)
- 重粒子線治療 (特集 知っておきたいがん放射線治療の知識)
- SY4-4 腎癌に対する重粒子線治療経験(4.腎癌治療の課題と新なる展開,シンポジウム,第99回日本泌尿器科学会総会)
- 会員のための企画 実質臓器悪性腫瘍に対する局所療法 重粒子線を用いたがん治療の現状と展望
- 臨床
- 重粒子線を用いたがん治療の現状と展望(実質臓器悪性腫瘍に対する局所療法,会員のための企画)
- 第1回 放医研-千葉県がんセンター合同シンポジウム 千葉県における難治性がんに対する診療・研究ネットワーク構築
- HIMAC15周年記念講演会 : 重粒子線がん治療の15年 5000例の治療成果