Study on Bone Formation Induced by Recombinant Human BMP-2 at Palatal Sites in Adult Rats
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概要
- 論文の詳細を見る
This study was designed to examine the effects of bone formation induced by recombinant human BMP-2 (rhBMP-2), which was implanted together with a polylactate-polyglycolate-copolymer/gelatine sponge (PGS) at palatal sites in 30-week-old male Wister rats. The rats were divided into four groups according to the dose of rhBMP-2: 0μg, 4μg, 8μg and 16μg. New bone formation was observed in every group, and new bone was continuous with the original bone at 6 weeks after implantation. Thickness of new bone (TNB) increased as the dose increased from 0μg to 8μg, reached the maximal level at 8μg. In contrast, TNB decreased significantly as the dose increased from 8μg to 16μg. The results of this study indicate that new bone formation varies according to the dose of rhBMP-2 at palatal sites in adult rats.
- 日本再生歯科医学会の論文
- 2006-09-30
著者
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NISHITANI Yoshihiro
Department of Operative Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pha
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YOSHIYAMA Masahiro
Department of Operative Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pha
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Yamaji Kozo
Department Of Operative Dentistry Field Of Study Of Biofunctional Recovery And Reconstruction Okayam
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Izawa Shunji
Department Of Operative Dentistry Field Of Study Of Biofunctional Recovery And Reconstruction Okayam
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ITOTA Toshiyuki
Department of Operative Dentistry,
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ITOTA Toshiyuki
Itota Dental Clinic
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Itota Toshiyuki
Department Of Operative Dentistry
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Itota Toshiyuki
Department Of Operative Dentistry Field Of Study Of Biofunctional Recovery And Reconstruction Okayam
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Yoshiyama Masahiro
Department Of Operative Dentistry Field Of Study Of Biofunctional Recovery And Reconstruction Okayam
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Yoshiyama Masahiro
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Nishitani Yoshihiro
Department Of Operative Dentistry Okayama University Graduate School Of Medicine Dentistry And Pharm
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Nishitani Yoshihiro
Department Of Operative Dentistry Field Of Study Of Biofunctional Recovery And Reconstruction Okayam
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Yamamoto Kazuyo
Osaka Dental Univ. Osaka Jpn
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Yoshiyama Masahiro
Department Of Operative Dentistry Okayama University Graduate School Of Medicine Dentistry And Pharm
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Yoshiyama Masahiro
Department Of Operative Dentistry Okayama University Graduate School Of Medicine Dentistry And Pharm
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Yoshiyama Masahiro
Department Of Operative Dentistry Okayama University Graduate School Of Medicine Dentistry And Pharm
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Yasuno Kenzo
Graduate School Of Dentistry (operative Dentistry) Osaka Dental University
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