各種組織の細胞質内Ca^<++>結合蛋白質とその分布

概要

論文の詳細を見る
The calcium ion (Ca^<++>), widely recognized as an important intracellular messenger in mammalian tissues, contributes to many cellular responses. Some processes regulated by calumodulin or other Ca^<++>-binding proteins are thought to play a central role in the intracellular calcium messenger system. In this study, using ^<45>Ca-autoradiography, we tried to detect Ca^<++>-binding proteins in cytosol of various organs in guinea pig, rat and mouse. It was detected Ca++_binding protein of MW 17kDa (calmodulin) in all organs. In brain and kidney, it was detected many Ca^<++>-binding proteins (brain : MW16k, 17k, 26k, 28k. 52kDa. kidney : MW 17k, 24kDa). Distribution of Ca^<++>-binding proteins among these animals was not different. It is suggested that Ca^<++>-binding proteins are tissue-specific and commonly distributed among these animals.
高知大学の論文
1987-12-10