歯周症を認めたWiison病の一剖検例

概要

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We sometimes encounter younger individuals suffered from diffuse resorption of the alveolar bone. In these cases, we can hardly confirm whether the cause of the changes are related with the local or general factors, and feel the difficulties of it's treatment. Otherwise a character of periodontal disease seems to be senile changes. In considering pathogenesis of periodontal disease, it is important to investigate younger individuals which show diffuse alveolar bone loss. The authosr report the pathohistological findings of the periodontium in an autopsy case of 13-year-old girl who had died of Wilson's disease. And the mandible was made into decalcified and undecalcified specimens. Radiologically, the disappearance of lamina dura and the widenning of the periodontal space could be seen. There were no gingival inflammations and pathological pocket formations. Histologically, edema and hialinization of the collagen fibers in the gingiva and the periodontal membrane could be seen. Vertical alveolar bone resorption was severe and it was mainly consisted of osteolysis. They are similar to the histological criterion of periodontosis. Such osteolysis could be seen in the other bones. Periodontal changes seem to be the local appearance of general changes. Arteriolosclerosis could be seen in the mandibular artery. It may be an accerating factor of the alveolar bone resorption.
特定非営利活動法人日本歯周病学会の論文
1980-03-28