Rationale and Design for a Study Using Intravascular Ultrasound to Evaluate Effects of Rosuvastatin on Coronary Artery Atheroma in Japanese Subjects : COSMOS Study (Coronary Atherosclerosis Study Measuring Effects of Rosuvastatin Using Intravascular Ultra

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概要

• 論文の詳細を見る

• Background There have been few multicenter studies using intravascular ultrasound (IVUS) to assess the process of atherosclerosis in a Japanese population with hypercholesterolemia that is being treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors for control of low-density lipoprotein-cholesterol. Methods and Results An open-label multicenter study is planned to evaluate with IVUS whether treatment with rosuvastatin for 76 weeks results in regression of coronary artery atheroma volume in patients who have coronary heart disease (CHD) and hypercholesterolemia. Sample size is 200 subjects with CHD who are to undergo percutaneous coronary intervention. The planned duration is between October 2005 and October 2008. Conclusions The COSMOS study will be the first multicenter cardiovascular study in a Japanese population and may provide new evidence on the effects of rosuvastatin on the progression of coronary atherosclerotic lesions.

• 社団法人日本循環器学会の論文
• 2007-01-20

著者

• MATSUZAKI Masunori

  Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate S

• DAIDA Hiroyuki

  Department of Cardiology, Juntendo University School of Medicine

• Takayama Tadateru

  Division of cardiology, Department of Medicine, Nihon University school of Medicine

• Saito satoshi

  Department of Medicine, Division of Cardiovascular Medicine, Nihon University School of Medicine

• Sato Sumiko

  Ehime Prefectural Central Hospital

• Matsuzaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• YAMAGUCHI Tetsu

  Toranomon Hospital

• Takayama Tadateru

  Division Of Cardiology Department Of Medicine Nihon University School Of Medicine

• Mitsui M

  Department Of Pediatrics And Child Health Nihon University School Of Medicine

• Yamagishi Masakazu

  Sumitomo Hospital

• YAMAGISHI Masakazu

  Kanazawa University Graduate School of Medicine

• Yamagishi Masakazu

  Division Of Cardiology First Department Of Medicine Osaka University School Of Medicine

• Hiro Takafumi

  Division Of Cardiology Department Of Medicine Nihon University School Of Medicine

• Matsubara Mitsunobu

  Department Of Medicine And Clinical Science Yamaguchi University Graduate School Of Medicine

• Miyahara Mitsuo

  The Second Department Of Internal Medicine Sapporo Medical College

• Yamaguchi Tetsu

  Cardiovascular Center, Toranomon Hospital

• Yamaguchi Tetsu

  Division Of Cardiology Showa University Fujigaoka Rehabilitation Hospital

• Daida Hiroyuki

  Department Of Cardiology

• Matsuzaki Masunori

  Department Of Cardiovascular Medicine Yamaguchi University Graduate School Of Medicine

• Takayama Tadateru

  Department Of Advanced Medical Science Nihon University School Of Medicine

• Yamasaki Masao

  Department Of Cardiovascular Medicine The Graduate School Of Medicine The University Of Tokyo

• Matsuzaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Graduate School Of Medicine Yamag

• Matsuzaki Masunori

  Department Of Medical Bioregulation Division Of Cardiovascular Medicine Yamaguchi University School

• Miyahara Mitsuo

  Dept. Of Intern. Med. (section 2) Sapporo Med. Coll.

• Matsuaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Hisaoka Takayuki

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Hiro Takafumi

  Division Of Cardiology Department Of Internal Medicine Nihon University School Of Medicine

• Yamashita Tsuminori

  Kagoshima City Medical Association Hospital

• Saito Satoshi

  Department Of Advanced Medical Science Nihon University School Of Medicine

• Takayama Tadateru

  Department Of Cardiovascular Surgery Nihon University School Of Medicine

• Miyahara Mitsuo

  Second Department Of Internal Medicine Sapporo Medical College

• Takayama Tadateru

  Department Of Cardiology Nihon University School Of Medicine Tokyo

• Yamaguchi Tetsu

  Kagoshima City Medical Association Hospital

• Yamagishi Masakazu

  Division Of Cardiology Department Of Internal Medicine Kanazawa University Graduate School Of Medici

• Matsuzaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Murakami Masanori

  The Second Division Of Internal Medicine Yamaguchi University School Of Medicine

• Yamaguchi Tetsu

  Cardiovascular Center Toranomon Hospital

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