MRI TRACER STUDY OF THE CEREBROSPINAL FLUID DRAINAGE PATHWAY IN NORMAL AND HYDROCEPHALIC GUINEA PIG BRAIN

スポンサーリンク

概要

• 論文の詳細を見る

• OBJECTIVE: Using magnetic resonance imaging (MRI), sequential information regarding the dynamic movement of the cerebrospinal fluid (CSF) from the subarachnoid space and the ventricles to the drainage pathway hi response to the CSF pressure was obtained in guinea pigs. In this study, a new mechanical hydrocephalus model in a guinea pig was developed to investigate the CSF kinetics hi an acute hydrocephalic brain. MATERIALS AND METHODS: A total of 18 adult male guinea pigs were studied. In the ventricular injection group, The CSF in the lateral and third ventricles was isolated by inserting a polyethylene tube with a cotton ball into the aqueduct of Sylvius. By infusing artificial CSF through this tubing acute ventriculomegaly was created. In the subarachnoid injection group, a polyethylene tube was placed at the cisterna magna. Using MRI with gadoteridol as a tracer, the movement of CSF from the subarachnoid space and dilated ventricles was monitored at various pressures. The CSF drainage pathway from the subarachnoid space in the hydrocephalic condition was examined and compared with the CSF drainage pathway in normal condition. RESULTS: Gadoteridol cleared from the lateral and third ventricles and reached the nasal mucosa via brain parenchyma; the movement was proportional to the CSF pressure. Gadoteridol from the subarachnoid space also reached the nasal mucosa and periorbital region in a similar manner. However, it was not observed to reach either over the convexity of the brain or adjacent to the superior sagittal sinus.

• 東海大学の論文

著者

• YAMADA Shinya

  Department of Physics, The University of Tokyo

• Yamada Shinya

  Department Of Neurosurgery Tokai University Oiso Hospital

• Yamada Shinya

  Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University

• SHIBATA Masayoshi

  Department of Biology, Tokyo Metropolitan University

• McCOMB J.

  Divisions of Neurosurgery, Childrens Hospital Los Angeles and The Keck School of Medicine, Universit

• Mccomb J.

  Division Of Neurosurgery Children's Hospital Los Angeles And The Keck School Of Medicine Univer

• SCADENG Merium

  Rudi Schulte Research Institute, Santa Barbara

• BLUML Stefan

  Division of Radiology, Children's Hospital Los Angeles and The Keck School of Medicine, University o

• NGUY Catherine

  Huntington Medical Research Institute, Pasadena

• ROSS Brian

  Huntington Medical Research Institute, Pasadena

• Bluml Stefan

  Division Of Radiology Children's Hospital Los Angeles And The Keck School Of Medicine Universit

• Nguy Catherine

  Huntington Medical Research Institute Pasadena

• Ross Brian

  Huntington Medical Research Institute Pasadena

• Scadeng Merium

  Rudi Schulte Research Institute Santa Barbara

• Shibata Masayoshi

  Department Of Neurosurgery Tokai University Hospital

• Shibata Masayoshi

  Department Of Biology Tokyo Metropolitan University

関連論文

• In-orbit performance of the hard X-ray detector on board Suzaku
• Suzaku Discovery of Absorption Lines from the Black Hole Transient 4U1630-472(Chapter 9. Stellar/Intermediate Mass Black Holes, The Extreme Universe in the Suzaku Era)
• Suzaku Discovery of Iron Absorption Lines in Outburst Spectra of the X-Ray Transient 4U 1630-472
• Knee Pain and its Associations with Age, Sex, Obesity, Occupation and Living Conditions in Rural Inhabitants of Japan
• INHIBITION OF IL-17 IS INVOLVED IN THE PATHOGENESIS OF INDOMETHACIN-INDUCED ENTERITIS IN MICE
• Microvascular Decompression for Hypertension : Clinical and Experimental Study
• Indications for Cisternal Drainage in Conjunction with Early Surgery for Ruptured Aneurysms and Timing of its Discontinuation
• BACH1 DEFCIENCY AMELIORATES DEXTRAN SULPHATE SODIUM-INDUCED COLITIS IN MICE
• アナナスショウジョウバエOm遺伝子座の細胞学的位置〔英文〕
• Painless Acute Aortic Dissection With a Left Hemiparesis : A Case Report
• Mechanism of Injury to the Corpus Callosum, With Particular Reference to the Anatomical Relationship Between Site of Injury and Adjacent Brain Structures
• Delayed ischemic neurological deficit of short duration in patients with subarachnoid hemorrhage
• PJ-374 Evaluation of Left Ventricular Function Using ECG-gated 16-slice MDCT : in Comparison to SPECT with Tc-tetrofosmin(CT/DSA-6 (I) PJ63,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• High Rates of Neurological Improvement Following Severe Traumatic Pediatric Spinal Cord Injury
• Total Synthesis of (-)-Decarestrictine J
• A METHOD TO ACCURATELY INJECT TUMOR CELLS INTO THE CAUDATE/PUTAMEN NUCLEI OF THE MOUSE BRAIN
• Prevention Strategy for Vibration Hazards by PortablePower Tools, National Forest Model of ComprehensivePrevention System in Japan
• MRI TRACER STUDY OF THE CEREBROSPINAL FLUID DRAINAGE PATHWAY IN NORMAL AND HYDROCEPHALIC GUINEA PIG BRAIN
• Do Liquid Crystal Displays Assure Better Readability than Cathode-Ray Tubes?
• Comparison of Readability between Liquid Crystal Displays and Cathode-Ray Tubes
• Daikenchuto, a Kampo Medicine, Regulates Intestinal Fibrosis Associated with Decreasing Expression of Heat Shock Protein 47 and Collagen Content in a Rat Colitis Model
• Toxic Megacolon Associated with Cytomegalovirus Infection in a Patient with Steroid-naïve Ulcerative Colitis
• High Sensitivity C-Reactive Protein Predicts Nonresponders and Cardiac Deaths in Severe Heart Failure Patients After CRT Implantation
• Intrathoracic Impedance Changes Reflect Reverse Left Ventricular Remodeling in Response to Cardiac Resynchronization Therapy in Chronic Heart Failure Patients
• Effect of Addition of Al to Single-Crystalline CoFe Electrodes on Nonlocal Spin Signals in Lateral Spin-Valve Devices
• Long-Term Increase of Intrathoracic Impedance after Cardiac Resynchronization Therapy Is Associated with Left Ventricular Reverse Remodeling
• Monitoring of Changes in Intrathoracic Impedance Is Useful for Predicting Decompensated Heart Failure
• Adaptive Servo Ventilation Improves not only Sympathetic Function but also Physical Performance: Results from New Multifunction Wireless Holter ECG
• Suzaku Discovery of Absorption Lines from the Black Hole Transient 4U1630-472
• Hypomagnesemia Associated with a Proton Pump Inhibitor
• Association between Characteristics of Left Ventricular Pacing Lead and Reverse Remodeling in Response to Cardiac Resynchronization Therapy
• Room-Temperature Tunneling Magnetoresistance in Magnetic Tunnel Junctions with a D0_{3}-Fe
• Molecular Beam Epitaxy of Co
• Sleep-Disordered Breathing Increases Risk for Fatal Ventricular Arrhythmias in Patients With Chronic Heart Failure
• Sleep-Disordered Breathing Increases Risk for Fatal Ventricular Arrhythmias in Patients With Chronic Heart Failure
• Dynamical Spin Injection into p-Type Germanium at Room Temperature

もっと見る 閉じる

スポンサーリンク