酵素の常温保存における耐湿性賦形剤の検討(平成16年度第50回低温生物工学会研究報告)

概要

論文の詳細を見る
Anhydrous amorphous raffinose and trehalose were examined their crystallinity in humid conditions by a powder X-ray diffractometer. The raffinose started to crystallize in the condition of 52% relative humidity at 35℃ after 49 hours and it crystallized completely after 304 hours. The trehalose crystallized completely in the same condition after 3 hours. Anhydrous amorphous raffinose is harder to crystallize than anhydrous amorphous trehalose. Glassy preservation of lactate dehydrogenase (LDH) was carried out in the humid conditions using these sugars as excipients. The enzyme in a trehalose system has a higher activity than in a raffinose system.
低温生物工学会の論文
2004-12-30