OCTを用いた生体レーザアブレーションのin situ観察

概要

論文の詳細を見る
When conducting laser ablation of biological tissue, a tomography of the tissue surface is necessary to measure the crater shape and crater depth, and observe damage to the surrounding tissue. In this paper, we demonstrate the in situ observation of biological tissue surfaces during laser ablation using optical coherence tomography (OCT). For the laser ablation of tissue, a Q-switched Nd: YAG laser is used as the light source, which supplies laser pulses of 10 ns at a wavelength of 1.06 μm and a repetition rate of 10 Hz. The OCT imaging optics consist of a low coherence interferometer where a 0.85-μm SLD is used as the light source, providing the spatial resolution of 18 μm. In the experiment, the crater depth of a human tooth is measured using these OCT images, and then the ablation rate of 0.21 μm/pulse is determined. Moreover, time-serial tomographic observation of the crater during laser ablation is carried out, showing all of the OCT images continuously.
社団法人日本生体医工学会の論文
2005-12-10