Vaginal Applicators (ovoids) for Local Control and Alleviation of Rectal Complications of Cervical Cancers Treated by Brachytherapy
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概要
- 論文の詳細を見る
To assess the effects of vaginal applicators (ovoids) on dose distribution, local control and rectal complications in cervical cancers treated by brachytherapy. Methods: From 1984 to 1992, 41 patients (15 stages I+II; 26 stages III+IV) were treated by high-dose-rate brachytherapy (20 Gy in 4 fractions) after external beam irradiation (36-56 Gy). Twenty-three patients were treated by standard application of both intrauterine tandem and ovoids, and 18 patients were treated by non-standard application. Results: The five-year, local-relapse-free rates by standard application and tandem alone were 69 and 65% overall; 83 and 100% for stages I+II; and 62 and 49% for stages III+IV. Local control was related to tumor response following the external beam irradiation and initial tumor size by multivariate analysis. Rectal complications seen in patients followed for more than 1 year were 33% after standard application and 22% for tandem use alone. The rectal doses given for standard application (24 Gy) and tandem use (16 Gy) were significantly different. Conclusions: The ovoid sources did not always contribute to local control, and occasionally led to rectal complications. The optimization of brachytherapy was dependent on patients' anatomy, tumor size, and tumor response.
- 東海大学の論文
著者
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AKIBA Takeshi
Department of Radiation Oncology, Tokai University School of Medicine
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母里 知之
東海大学 放射線
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SHINOZUKA Takao
Department of Gynecology, School of Medicine, Tokai University
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Akiba Takeshi
Department Of Radiation Oncology Tokai University School Of Medicine
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大泉 幸雄
東海大学医学部放射線科学教室
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MORI Tomoyuki
Department of Radiology, School of Medicine, Tokai University
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Shinozuka Takao
Department Of Gynecology Ayase Kosei Hospital
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Shinozuka Takao
Department Of Obstetrics And Gynecology Tokai University School Of Medicine
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OHIZUMI Yukio
Department of Radiation Oncology, Tokai University School of Medicine
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TAMAI Yoshifumi
Department of Radiation Oncology, Tokai University School of Medicine
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IMAMIYA Satoshi
Department of Radiation Oncology, Tokai University School of Medicine
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Oizumi Yukio
Department Of Radiation Oncology Tokai University School Of Medicine
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Mori Tomoyuki
Department Of Radiation Oncology Tokai University School Of Medicine
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Mori Tomoyuki
Department Of Biomolecular Sciences Saga Medical School
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Tamai Yoshifumi
Department Of Radiation Oncology Tokai University School Of Medicine
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Mori Tomoyuki
Dept. Radiation Oncology
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母里 知之
Department Of Radiation Oncology Tokai University School Of Medicine
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Imamiya Satoshi
Dept. Radiat. Oncol. Univ. Tokai
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Imamiya Satoshi
Department Of Radiation Oncology Tokai University School Of Medicine
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Mori Tomoyuki
Dept. Radiat. Oncol. Tokai Univ. Sch. Med.
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Ohizumi Yukio
Department Of Radiation Oncology Tokai University School Of Medicine
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Ohizumi Yukio
Department Of Radiation Oncology School Of Medicine Tokai University
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