A Pregnant Case of Severe Acute Hepatitis Type C Successfully Treatedwith Natural Interferon-Alpha and Showing No Evidence of a MaternalTransmission of HCV to the Newborn
スポンサーリンク
概要
- 論文の詳細を見る
We report here a case of a 21-year-old Japanese woman suffering from severe acute liver injury due to hepatitis C virus (HCV) infection in the third trimester of her first pregnancy. When a second-generation antibody reactivity to HCV had not yet appeared, HCV RNA was detected in her serum using a polymerase chain reaction. Subsequent natural interferon-alpha therapy played a key role in the recovery from severe hepatic injury, and the disappearance of HCV RNA in her serum. Consequently, HCV RNA has not been detected for over 17 months after the cessation of interferon administration. On the other hand HCV RNA was not detected in her cord or the baby serum. Therefore, maternal transmission of HCV was not evidenced. This is a rare case in which a severe form of acute hepatitis C was successfully treated with natural interferon-alpha, and no indication of a maternal transmission of HCV in acute hepatitis C could be demonstrated with polymerase chain reaction analysis.
- 新潟大学の論文
著者
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Tanaka K
Department Of Obstetrics And Gynecology Niigata University Graduate School Of Medical And Dental Sci
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Aoyagi Y
The Third Division Department Of Internal Medicine Niigata University School
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AOYAGI Yutaka
The Third Department of Internal Medicine,Chiba University School of Medicine
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Aoyagi Yutaka
新潟大学 医歯学総合研究科消化器内科学
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SUDA Takeshi
The Third Division, Department of Internal Medicine, Niigata University School of Medicine
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Asakura H
Niigata Univ. Graduate School Of Medical And Dental Sci. Niigata Jpn
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Suda T
Niigata Univ. Graduate School Of Medical And Dental Sci. Niigata Jpn
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Takeyasu Suda
The First Department Of Surgery Niigata University School Of Medicine
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Yutaka Aoyagi
The Third Division Department Of Internal Medicine Niigata Universityschool Of Medicine
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Nomoto Minoru
Department Of Internal Medicine Iii Niigata University School Of Medicine
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Ohkoshi S
Division Of Gastroenterology And Hepatology Niigata University Graduate School Of Medical And Dental
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Asakura Hitoshi
Division Of Hepatology And Gastroenterology Niigata University Graduate School Of Medical And Dental
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Takeshi SUDA
The Third Division, Department of Internal Medicine, Niigata UniversitySchool
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Shogo OHKOSHI
The Third Division, Department of Internal Medicine, NiigataUniversity School
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Aoyagi Yutaka
Third Department Of Internal Medicine Niigata University School Of Medicine
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Takeshi Suda
The Third Division Department Of Internal Medicine Niigata Universityschool
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OHKOSHI Shogo
The Third Division, Department of Internal Medicine, NiigataUniversity School
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AOYAGI Yutaka
the Third Department of Internal Medicine, Chiba University School of Medicine
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