Diterpenoids. XXVI. Synthesis of 11-Methoxy-diterpenoids. (1). Synthesis of Antipodal 11-Methoxy-deoxypodocarpic Acid Derivatives
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概要
- 論文の詳細を見る
7-Oxo esters (IV) and (V) derived from l-abietic acid (III) were converted to half esters (XI) and (XV), respectively. Intramolecular cyclization of XV gave the expected 11-methoxy oxo ester (XVI), but that of XI yielded the undesirable bicyclo[3,3,1]nonane ester (XVII) via a methoxy migration of the methoxy carbonyl group. 11-Hydroxy diterpenoid is not only a potential intermediate for the syntheses of taxodione (I) and callicarpone (II), but also is regarded as an important substance for an oxidative substitution of A-ring or 10-methyl group from its 11-hydroxyl group.
- 公益社団法人日本薬学会の論文
- 1973-03-25
著者
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田原 昭
Rikagaku Kenkyusho (The Institute of Physical and Chemical Research)
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大塚 晏央
Rikagaku Kenkyusho
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田原 昭
Rikagaku Kenkyusho (the Institute Of Physical Chemical Research)
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大塚 晏央
Rikagaku Kenkyusho (the Institute Of Physical Chemical Research)
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- Novel Nitration Reaction of Methyl 7-Oxodehydroabietate
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- Diterpenoids. X. A Synthesis of c-Homohydrofluorene
- Diterpenoids. XLVI. Syntheses of Taxodione, Royleanone and Their Analogues
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