Some Observations on the Metabolites of Phoma Species

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概要

• 論文の詳細を見る

• Fifteen strains of Phoma species were examined for their production of toxic metabolite (s). Although three of them showed the toxicity for cultured HeLa cells and mice and the metabolites were not identical with the known metabolites, attempts to isolate toxic principle (s) were abandoned due to their instability. In the course of the work cynodontin (3), 6-methylsalicylic acid, an unidentified phenolic of mp 191-193°, and a chromanone (4) were isolated. The chromanone (4) was proved to be (2R)-5-hydroxy-6-(2'-hydroxyethyl)-7-methoxy-2-methylchromanone.

• 社団法人日本薬学会の論文
• 1973-10-25

著者

• 関田 節子

  国立衛生試験所

• 梅田 誠

  Tissue Culture Laboratory Yokohama City University School Of Medicine

• 斎藤 守

  Institute Of Medical Sciences University Of Tokyo

• 宇田川 俊一

  Nodai Research Institute, Tokyo University of Agriculture

• 高橋 千加子

  National Institute of Hygienic Sciences

• 名取 信策

  国立衛試

• 高橋 千加子

  Institute of Medical Sciences

• 関田 節子

  Institute of Medical Sciences

• 義平 邦利

  Institute of Medical Sciences

• 名取 信策

  Institute of Medical Sciences

• 宇田川 俊一

  Institute of Medical Sciences

• 倉田 浩

  National Institute of Hygienic Sciences, Institute of Medical Sciences

• 榎本 眞

  Institute of Medical Sciences

• 大坪 浩一郎

  Institute of Medical Sciences

• 梅田 誠

  Institute of Medical Sciences

• 斎藤 守

  University of Tokyo, Institute of Medical Sciences

• 名取 信策

  National Institute Of Hygienic Sciences:(present Address)meiji College Of Pharmacy

• 関田 節子

  National Institute Of Hygienic Sciences

• 榎本 眞

  Institute Of Medical Sciences University Of Tokyo

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