1-置換2-ピペリドン類と塩化ホスホリルとの反応(第3報) : 反応生成物の構造その3 : 4級塩の還元
スポンサーリンク
概要
- 論文の詳細を見る
1,5-Dibenzyl-2,3,4,4a, 5,6,7,8 (or 2,3,4,5,6,7,8,8a)-octahydrocyclobuta [1,2-b : 3,4-b'] dipyridin-1-ium halide (IIb) was reduced in different conditions to give six kinds of products of which structures except VI were elucidated. Catalytic hydrogenation of IIb in the presence of platinum afforded 1,5-dibenzylper-hydrocyclobuta [1,2-b : 3,4-b'] dipyridine-A (III), 1,1'-dibenzyl-epi-2,3'-bipiperidine (IV), 1,1'-dibenzyl-2,3'-bipiperidine (V), N, N-dibenzyl-4-methyl-1,9-nonanediamine (VII), and C_<24>H_<34>N_2 (VI). By reduction of IIb with sodium borohydride in methanol, III, IV, and V were formed, while by the same operation in tetrahydrofuran instead of methanol, III and its isomer-B (VIII) were produced.
- 公益社団法人日本薬学会の論文
- 1969-08-25
著者
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赤星 三彌
Research Laboratories, Ohta Pharmaceutical Co., Ltd.,
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赤星 三彌
Research Laboratories Ohta Pharmaceutical Co. Ltd.
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久津間 輝雄
Research Laboratories Ohta Pharmaceutical Co. Ltd.:(present Address) Research Laboratories Fujirebio
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赤星 三彌
東京大学薬学部
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久津間 輝雄
東京大学薬学部
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