Cimicifuga属植物の成分研究(第3報) : オオバショウマの成分その3 Acerinolの構造

概要

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Acerinol (I), m.p. 152〜153°, [α]^<24>_D+25.65°, C_<30>H_<46>O_5,is a triterpene alcohol obtained on acid treatment of the glycosidic fraction of Cimicifuga acerina. I forms a monoacetate (II) of m.p. 270〜272°, [α]^<24>_D+33.84°, C_<32>H_<48>O_6,a diacetate (III) of m.p. 214〜216°, C_<34>H_<50>O_7,a monoketo compound (IV) of m.p. 185〜187°, C_<30>H_<44>O_5,and a dehydrated compound (V) of m.p. 170〜172°, C_<30>H_<44>O_4. Catalytic reduction of V affords a dihydro compound (VI) of m.p. 169〜171°, C_<30>H_<45>O_4,I also forms a monoepoxy compound (VII) of m.p. 148〜150°, C_<30>H_<46>O_6,whose acid treatment produces a diene compound (VIII) of m.p. 138〜140°, C_<30>H_<44>O_5. From these reactivities and from other observations, it was concluded that I should be a kind of lanostane series compound represented by formula I.
社団法人日本薬学会の論文
1967-12-25