防已科植物アルカロイド研究(第225報) : Dauricine型塩基の合成その2 : 2,7-Bis(2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-ylmethyl)dibenzo-p-dioxinの合成とその液安ナトリウム開裂反応
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概要
- 論文の詳細を見る
The title compound, 2,7-bis(2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-ylmethyl)-dibenzo-p-dioxin (IX), was synthesized by the Bischler Napieralski reaction of N, N'-bis(3,4-dimethoxyphenethyl) dibenzo-p-dioxin-2,7-diacetamide (VI). This compound was identified with the non-phenolic product from the Ullmann condensation of dl-armepavine and dl-3'-bromo-4'-O-acetylarmepavine. Cleavage reaction of IX with sodium in liquid ammonia afforded dauricine-type bases (X and XI).
- 公益社団法人日本薬学会の論文
- 1966-08-25
著者
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正木 幸雄
Faculty of Pharmaceutical Sciences, Kyoto University
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正木 幸雄
Faculty Of Pharmaceutical Sciences Kyoto University
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冨士谷 憲徳
京都大学薬学部
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正木 幸雄
京都大学薬学部
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冨士谷 憲徳
Kyoto Pharmaceutical University
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