Azabenzo[c]quinolizine類の合成研究(第5報) : 5,6-Dihydro-3-ethoxycarbonyl-4-hydroxy-2-methyl-4aH-pyridazo[2,3-α]quinoline類の合成
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概要
- 論文の詳細を見る
Ethyl 1-(ethoxycarbonylisopropylidene)amino-1,2,3,4-tetrahydro-2-quinolinecarboxylate (IV), obtained by heating ethyl 1-amino-1,2,3,4-tetrahydro-2-quinolinecarboxylate with ethyl aceto-acetate, was cyclized to the corresponding keto ester (V, Va, or Vb) at 110°, in the presence of sodium ethoxide. The difference between Va and Vb lies in the presence of an intra-molecular hydrogen bonding in Va and a free enol form of keto ester in Vb.
- 公益社団法人日本薬学会の論文
- 1966-07-25
著者
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永田 正典
Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University
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永田 正典
Faculty Of Pharmaceutical Sciences University Of Toyama
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