イソプレノイドキノン類の高速液体クロマトグラフィー(第1報) : フィロキノン, メナキノン-4,ユビキノン-10の同族体, 幾何異性体および分解物の分離

概要

論文の詳細を見る
In an attempt to separate homologues, cis-trans isomers, and decomposition products of the isoprenoid quinones, phylloquinone, menaquinone-4,and ubiquinone-10,high-speed liquid chromatographic method was investigated. Homologues of the isoprenoid quinones could be separated by using Permaphase ODS with methanol-water or dioxane-water. In both mobile phases, the plot of log k'vs. the number of carbon atoms in the isoprenoid side chain gave a linear relationship. Separation of decomposition products of the isoprenoid quinones was also achieved using the same condition as above. In the case of phylloquinone and menaquinone-4,the plot of log V_R of the decomposition products vs. percent modifier gave a linear relationship. cis-trans isomers of the isoprenoid quinones was separated using Zorbax SIL with isopropyl ether-n-hexane.
社団法人日本薬学会の論文
1977-05-25