活性エステルとして4-Morpholyl Esterのペプチド合成への応用
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概要
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Esters of several carbobenzoxyamino acids with 4-hydroxymorpholine were prepared by direct condensation using dicyclohexylcarbodiimide (Table I). The esters obtained were crystalline solid and reacted readily with amino acid ester hydrochlorides in the presence of sodium acetate (or triethylamine with acetic acid) to form the corresponding carbobenzoxydipeptide esters (Table II). Presence of racemate (ca.0.6%) was observed by Anderson's test.
- 公益社団法人日本薬学会の論文
- 1973-03-25
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- タフトシン関連ペプチドの合成(第2報)
- タフトシン関連ペプチドの合成(第1報)
- 活性エステルとして4-Morpholinyl Esterのペプチド合成への応用(第4報)
- 活性エステルとして4-Morpholinyl Esterのペプチド合成への応用(第3報)
- 活性エステルとして4-Morpholinyl Esterのペプチド合成への応用(第2報)
- 活性エステルとして4-Morpholyl Esterのペプチド合成への応用