In Vivo Electron Spin Resonance Assessment of Dacay Constant of Nitroxyl Radical in Selenium-Deficient Rat
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概要
- 論文の詳細を見る
In vivo reducing capacity and cytosolic glutathione peroxidase (GSH-Px) activity in liver homogenate were evaluated in 6 weeks old Se-deficient and normal rats. GSH-Px was significantly lower in Se-deficient rats than in normal rats. In vivo reducing capacity in head and liver parts, estimated from in vivo signal decay of a nitroxyl spin probe using a low frequency (300 MHz) ESR spectrometer, was significantly decreased in Se-deficient rats, suggesting a decrease of antioxidant capacity in Se-deficient rats.
- 公益社団法人日本薬学会の論文
- 2000-05-01
著者
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Endo Kazutoyo
Department Of Physical Chemistry Showa Pharmaceutical University
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Matsumoto Ken-ichiro
Department of Physical Chemistry, Showa Pharmaceutical University
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UTSUMI HIDEO
Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University
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Utsumi H
Department Of Biophysics Graduate School Of Pharmaceutical Sciences Kyushu University
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Utsumi Hideo
Department Of Bio-functional Science Graduate School Of Pharmaceutical Sciences Kyushu University
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Matsumoto Ken-ichiro
Department Of Physical Chemistry Showa Pharmaceutical University
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Utsumi Hideo
Department of Bio-Function Science, Faculty of Pharmaceutical Science, Kyushu University
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