Intramolecular Ring Formation of Phenyl Azide and Furan Moieties
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概要
- 論文の詳細を見る
Thermal decompositions of methyl 5-[2-(2-azidophenyl) ethyl]-2-furoate (3a), methyl 5-[2-(2-azido-4,5-methylenedioxyphenyl) ethyl]-2-furoate (3b) and methyl 5-[2-(2-azido-4,5-dimethoxyphenyl) ethyl]-2-furoate (3c) gave methyl pyrrolo [1,2-a] quinoline-3-carboxylates (10a-c) ; in the case of 3a, the 4,5-dihydro product 9 was also obtained. Photochemical decompositions of 3a and 3b in ethanol gave methyl 4,5-dihydro-1-ethoxypyrrolo [1,2-a]-quinoline-3-carboxylates (15a, b). In contrast, the cyclization product was not detected from 3c under similar conditions. Methyl 5-(2-azido-4,5-dimethoxybenzyl)-2-furoate (8) gave 7,8-dimethoxypyrido-[1,2-a] indole-1,2-dione (22) on thermolysis, and on photolysis in ethanol, gave methyl 6,7-dimethoxy-9H-pyrrolo [1,2-a] indole-3-carboxylate (23), trans-methyl 3-(6,7-dimethoxy-3-hydroxy-2-quinolyl) acrylate (25) and 22. The pathways of these of these reactions are discussed.
- 社団法人日本薬学会の論文
- 1982-01-25
著者
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古川 宏
名城大・薬
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古川 宏
Faculty of Pharmacy, Meijo University
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薬師神 健一
Faculty Of Pharmacy Meiji University
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古川 宏
Faculty Of Pharmacy Meijo University
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鶴田 豊久
Faculty of Pharmacy, Meijo University
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薬師神 健一
名城大学薬学部
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鶴田 豊久
Faculty Of Pharmacy Meijo University
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