Studies on Phosphonic Acid Antibiotics. IV. Synthesis and Antibacterial Activity of Analogs of 3-(N-Acetyl-N-hydroxyamino)-propylphosphonic Acid (FR-900098)
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概要
- 論文の詳細を見る
The synthesis of analogs of 3-(N-acetyl-N-hydroxyamino) propylphosphonic acid (FR-900098,Ia) and an analysis of their structure-activity relationship are described. Among them, compounds Ib (FR-31564) and XIIb (FR-32863) have recently been found to be produced naturally by Streptomyces lavendulae. The antibacterial activity of Ib against Pseudomonas species is especially significant.
- 公益社団法人日本薬学会の論文
- 1982-01-25
著者
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紙谷 孝
Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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橋本 真志
Research Laboratories, Fujisawa pharmaceutical Co., Ltd.
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武野 秀一
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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逸見 恵次
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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紙谷 孝
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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橋本 真志
Exploratory Research Laboratories Fujisativa Pharmaceutical Co. Ltd.
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逸見 恵次
Research Laboratories, Fuiisawa Pharmaceutical Co., Ltd.
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武野 秀一
Research Laboratories, Fuiisawa Pharmaceutical Co., Ltd.
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紙谷 孝
Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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