SYNTHESIS AND IMMUNOSTIMULATING ACTIVITY OF FK-156 ANALOGUES : FATTY ACID DERIVATIVES OF N-[N^α-(γ-D-GLUTAMYL)-L-LYSYL]-D-ALANINE
スポンサーリンク
概要
- 論文の詳細を見る
The fatty acid derivatives 3a, b of bacterial cell-wall peptidoglycan peptides related to FK-156 (1) were synthesized and their immunostimulating activities were examined. The new compounds 3a, b showed significant antiinfectious potencies comparable to that of 1 and 3b especially exhibited a potent tumor-suppressive property lacking in 1.
- 公益社団法人日本薬学会の論文
- 1982-08-25
著者
-
岡田 達
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
武野 秀一
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Hemmi K
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
北浦 良彦
(Present address)Pfizer Central Research
-
中口 修
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
北浦 良彦
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
武雄 秀一
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
岡田 達
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
中口 修
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
Hemmi Keiji
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
Mine Yasuhiro
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
Mori Joh
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
Hashimoto Masashi
Central Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
-
Mori Joh
Central Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Mine Yasuhiro
Central Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Hashimoto M
Exploratory Research Laboratories Fujisawa Phamaceutical Co. Ltd. :(present Address)tsukuba Research
-
中口 修
藤沢薬品工業
関連論文
- 4-(1-Benzoylindol-3-yl)butyric Acids and FK143 : Novel Nonsteroidal Inhibitors of Steroid 5α-Reductase (II)
- (1-Benzylinodole-3-yl)alkanoic Acids : Novel Nonsteroidal Inhibitors of Steroid 5α-Reductase (I)
- SYNTHESIS OF 1-DEOXYNOJIRIMYCIN AND 1-DEOXYMANNOJIRIMYCIN
- Synthesis and Aldose Reductase-Inhibitory Activities of Structural Analogues of WF-3681,a Novel Aldose Reductase Inhibitor
- Enantioselective Synthesis of Monocyclic β-Lactams Related to Nocardicins via a [2+2] Cycloaddition Reaction(Organic,Chemical)
- Preparation of 3-Aminonocardicinic Acid and Its Acyl Derivatives(Organic,Chemical)
- AN EFFICIENT SYNTHESIS OF WF-3681, A NOVEL ALDOSE REDUCTASE INHIBITOR, AND ITS RELATED COMPOUNDS(Communications to the Editor)
- 43 ペニシリンよりModified β-lactam Antibioticsへの変換
- Synthesis of Some Polyhydroxylated Pyrrolidine Derivatives(Organic,Chemical)
- SYNTHESIS AND ADJUVANT ACTIVITY OF FK-156 ANALOGUES : ACYL DERIVATIVES OF N-[N^2-(L-ALANYL-γ-D-GLUTAMYL)-2 (L), 2'(D)-DIAMINO-1-PIMELOYL] GLYCINE
- Studies on Structure-Activity Relationships of FK-156,an Immunostimulating Peptide, and Related Compounds. II. Synthesis of N^2-(γ-D-Glutamyl)-2 (L), 2' (D)-diaminopimelic Acid as the Minimal Essential Structure of FK-156
- Studies on Structure-Activity Relationships of FK-156,an Immunostimulating Peptide, and Related Compounds. I. Synthesis of Stereoisomeric Analogues of FK-156
- SYNTHESIS AND IMMUNOSTIMULATING ACTIVITY OF FK-156 ANALOGUES : FATTY ACID DERIVATIVES OF N-[N^α-(γ-D-GLUTAMYL)-L-LYSYL]-D-ALANINE
- Studies on Phosphonic Acid Antibiotics. IV. Synthesis and Antibacterial Activity of Analogs of 3-(N-Acetyl-N-hydroxyamino)-propylphosphonic Acid (FR-900098)
- 76 免疫増強作用を有する微生物代謝産物Gludapcin(FK-156)の合成
- Studies on Phosphonic Acid Antibiotics. III. Structure and Synthesis of 3-(N-Acetyl-N-hydroxyamino) propylphosphonic Acid (FR-900098) and 3-(N-Acetyl-N-hydroxyamino)-2 (R)-hydroxypropyl-phosphonic Acid (FR-33289)
- Synthesis and Characterization of Orally Active Nonpeptide Vasopressin V_2 Receptor Antagonists