Synthetic Cephalosporins. VII. Synthesis and Antibacterial Activity of 7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(3-(3-hydroxy-4-pyridon-1-yl)-3-carboxypropoxyimino)acetamide]-(1,2,3-thiadiazol-5-yl)-thiomethyl-3-cephem-4-carboxylic Acid and Its Related Compounds
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概要
- 論文の詳細を見る
Synthesis and antibacterial activity of 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(3-(3-hydroxy-4-pyridon-1-yl)-3-carboxypropoxyimino)acetamide-3-(1,2,3-thiadiazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid (12a) and its related compounds are described. Compound 12a exhibited excellent antibacterial activity against gram-negative bacteria, including Pseudomonas aeruginosa.
- 公益社団法人日本薬学会の論文
- 1990-12-25
著者
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畠中 稔
The Institute of Scientific and Industrial Research, Osaka University
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畠中 稔
The Institute Of Scientific And Industrial Research Osaka University
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坂上 健司
Pharmaceutical Research Center, Meiji Seika Kaish , Ltd.,
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岩松 勝義
Pharmaceutical Research Center, Meiji Seika Kaish , Ltd.,
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渥美 國夫
Pharmaceutical Research Center, Meiji Seika Kaish , Ltd.,
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渥美 國夫
Pharmaceutical Research Center Meiji Seika Kaisha Ltd.
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渥美 國夫
明治製菓株式会社 薬品総合研究所 創薬研究所
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坂上 健司
Pharmaceutical Research Center Meiji Seika Kaisha Ltd.
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岩松 勝義
Pharmaceutical Research Center Meiji Seika Kaish Ltd.
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