Acceleration of the Copper-catalyzed Autoxidation of Cysteine by Ethylenediaminetetraacetic Acid and Related Polyaminopolycarboxylic Acids
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概要
- 論文の詳細を見る
Polyaminopolycarboxylic acid with at least two ligand nitrogens such as ethylenediaminetetraacetic acid accelerates the copper-catalyzed autoxidation of cysteine. The extent of acceleration of the reaction is related to the stability constant of the Cu (II) chelate of the polyaminopolycarboxylic acid. N-Hydroxyethylethylenediaminetriacetic acid, N-hydroxy-1,3-diaminopropanetetraacetic acid and ethyleneglycol-bis-(β-aminoethylether) tetraacetic acid are the most potent accelerators and those chelating agents have the stability constants of approximately 10^<17.5>. Addition of a sufficient excess of the chelating agent over cysteine retards the oxidation.
- 公益社団法人日本薬学会の論文
- 1978-01-25
著者
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花木 昭
National Institute of Radiological Sciences
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花木 昭
Faculty Of Engineering Shizuoka University
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Hanaki A
Faculty Of Engineering Shizuoka University
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上出 鴻子
National Institute of Radiological Sciences
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