Synthesis of Active Forms of Vitamin D. VIII. Synthesis of [24R] -and [24S] -1α, 24,25-Trihydroxyvitamin D_3
スポンサーリンク
概要
- 論文の詳細を見る
24ξ, 25-Dihydroxycholesterol was converted, through 1,4,6-trien-3-one and its 1α, 2α-epoxide, into 1α, 24ξ, 25-trihydroxycholesterol. After resolution of C-24 epimers and determining their configurations, both isomers were led to [24R]- and [24S]-1α, 24,25-trihydroxyvitamin D_3 by bromination, dehydrobromination and ultraviolet-irradiation.
- 1975-03-25
著者
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池川 信夫
Laboratory Of Chemistry For Natural Products Tokyo Institute Of Technology
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池川 信夫
東京工大 理
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竹下 徹
Teijin Institute for Biomedical Research
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森崎 益雄
Laboratory of Chemistry for Natural Products, Tokyo Institute of Technology
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小泉 直之
Laboratory of Chemistry for Natural Products, Tokyo Institute of Technology
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竹下 徹
Teijin Institute Of Biomedical Research
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竹下 徹
Teijin Institute For Bio-medical Research
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小泉 直之
Department Of Chemistry Tokyo Institute Of Technology:(present Address)teikoku Hormone Mfg. Co. Ltd.
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加藤 喜規
Teijin Institute for Biomedical Research, Hino-shi, Tokyo
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加藤 喜規
Teijin Institute For Biomedical Research Hino-shi Tokyo
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