Radioprotective Effect of Sodium Hydrogen S-(2-L-Pyrrolidyl-methyl) phosphorothioate in Mice
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概要
- 論文の詳細を見る
Several aminoethyl and pyrrolidylmethyl thiosulfate and thiophosphate derivatives were synthesized and tested for the radioprotective effect in X-irradiated mice. Sodium hydrogen S-(L-2-pyrrolidylmethyl) phosphorothioate was most protective among ten compounds tested. It was effective to a same extent as cysteamine which is a typical radioprotector. N-Methylpyrrolidyl derivative of the compound was completely inactive. Furthermore, no radioprotection was observed in case of the corresponding thiosulfate.
- 公益社団法人日本薬学会の論文
- 1973-12-25
著者
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高木 良成
放射線医学総合研究所薬学研究部
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高木 良成
National Institute Of Radiological Sciences
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赤星 三弥
National Institute of Radiological Sciences
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赤星 三弥
Research Laboratories, Ohta Pharmaceutical Co., Ltd.
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石井 伸彦
National Institute of Radiological Sciences
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井手 至
National Institute of Radiological Sciences
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井手 至
National Institute Of Radiological Sciences:(present Address)hoshi College Of Pharmacy
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赤星 三弥
太田薬品
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