Studies on the Stereochemistry of Emetine. III. Absolute Stereochemical Configuration of Emetine
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概要
- 論文の詳細を見る
The results of acid catalyzed epimerization of (-)-2'-benzoylemetine, which possesses the same configuration as the original alkaloid, and of reduction of 2'-benzoyl-5,11b-dehydroemetinium salt, and the presence of trans-quinolizidine bands in infrared spectra of (-)-2'-acylemetines suggested that (-)-emetine should be represented by (Ia) or (IV), alternatively. The large negative contribution of C-11b hydrogen of (-)-2'-acylemetine to the [M]_D value gave evidence for (Ia) as the absolute configuration of (-)-emetine.
- 公益社団法人日本薬学会の論文
- 1960-06-25
著者
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寺島 正直
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
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寺島 正直
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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寺島 正直
Pharmaceutical Institute Medical Faculty University Of Tokyo
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