A New Synthetic Route towards the Mono-O-protected Anticonformationally Constrained Pyrimidine Acyclic Nucleoside
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概要
- 論文の詳細を見る
Novel synthetic approach to mono-O-protected anti-conformationally constrained pyrimidine acyclic nucleoside was attained from the coupling of lithiated 2,4-dimethoxy-6-methylpyrimidine with 1-benzyloxy-3-(tert-butyldiphenylsilyloxy)propan-2-one, followed by the sequential reactions of methylthiomethylation, cyclization, hydroxylation, and dealkylation.
- 公益社団法人日本薬学会の論文
- 2002-08-01
著者
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HSU Ling-Yih
School of Pharmacy, National Defense Medical Center
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Hsu Ling-yih
School Of Pharmacy National Defense Medical Center
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LIU Chi-Tsan
School of Pharmacy, National Defense Medical Center
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Liu Chi-tsan
School Of Pharmacy National Defense Medical Center
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TU Tsu-Chiang
Department of Pharmacy, Tri-Service General Hospital
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Tu Tsu-chiang
Department Of Pharmacy Tri-service General Hospital
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- A New Synthetic Route towards the Mono-O-protected Anticonformationally Constrained Pyrimidine Acyclic Nucleoside
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