Chemical Modification of Coumarin Dimer and HIV-1 Integrase Inhibitory Activity

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概要

• 論文の詳細を見る

• A systematic series of chemically modified coumarin dimmers has been synthesized and tested for their inhibitory activity against HIV-1 integrase. We observed that modified coumarin dimmers containing hydrophobic moiety on the linker display potent inhibitory activities.

• 公益社団法人日本薬学会の論文
• 2002-12-01

著者

• MOUSCADET Jean-Francois

  L.B.P.A, CNRS UMR8532, Ecole Normale Superieure de Cachan

• HSU Ling-Yih

  School of Pharmacy, National Defense Medical Center

• Hsu L‐y

  National Defense Medical Center Twn

• Hsu Ling-yih

  School Of Pharmacy National Defense Medical Center

• MAO Pili

  Department of Pharmacy, Veterans General Hospital Kaohsiung

• LEH Herve

  L.B.P.A CNRS UMR8532, Ecole Normale Superieure de Cachan

• AUCLAIR Christian

  L.B.P.A CNRS UMR8532, Ecole Normale Superieure de Cachan

• Mao P

  Department Of Pharmacy Veterans General Hospital Kaohsiung

• Leh H

  L.b.p.a Cnrs Umr8532 Ecole Normale Superieure De Cachan

• Auclair C

  L.b.p.a Cnrs Umr8532 Ecole Normale Superieure De Cachan

• Mouscadet J‐f

  L.b.p.a Cnrs Umr8532 Ecole Normale Superieure De Cachan

• Mouscadet Jean-Francois

  L.B.P.A CNRS UMR8532, Ecole Normale Superieure de Cachan

関連論文

• HIV-1 Integrase Inhibition of Biscoumarin Analogues
• Evaluation of Polyphenolic Acid Esters as Potential Antioxidants(Medicinal Chemistry)
• Synthesis and Biological Evaluation of Ebselen and Its Acyclic Derivatives
• Synthesis and Biological Activity of Sulfur-Containing Aryl-aldehyde Schiff Bases
• A New Synthetic Route towards the Mono-O-protected Anticonformationally Constrained Pyrimidine Acyclic Nucleoside
• Chemical Modification of Coumarin Dimer and HIV-1 Integrase Inhibitory Activity

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