Synthesis of Hexahydropyridazine-3-phosphonic Acid

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The synthesis of hexahydropyridazine-3-phosphonic acid (piperidazine-3-phosphonic acid) was performed via a hetero-Diels-Alder reaction followed by Lewis acid-catalyzed phosphonylation. This two-step procedure was improved to a one-pot reaction.
公益社団法人日本薬学会の論文
2004-01-01

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